Sugi Predict

Sugi Predict / Compounds / SCHEMBL29625818

SCHEMBL29625818

SCHEMBL29625818

CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ AGTR2 P50052 5/20 0.63
▸ AGTR1 P30556 4/20 0.63
▸ FCGRT P55899 4/20 0.55
▸ NPY2R P49146 5/20 0.54
▸ NPY4R P50391 5/20 0.54
▸ NPY5R Q15761 5/20 0.54
▸ NPY1R P25929 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31339335 0.83 AGTR2 (0.77) AGTR2AGTR1
Angiotensin Amide SCHEMBL27944927 0.80 AGTR2 (0.88) AGTR2AGTR1
[Val5] - Angiotensin Ii SCHEMBL31572111 0.80 AGTR2 (0.94) AGTR2AGTR1
SCHEMBL29506656 0.80 FCGRT (0.71) AGTR2AGTR1FCGRT
SCHEMBL29402986 0.80 AGTR1 (0.65) AGTR2AGTR1NPY2RNPY4RNPY5R
SCHEMBL30337899 0.79 AGTR1 (0.69) AGTR2AGTR1
SCHEMBL29599255 0.79 AGTR2 (0.90) AGTR2AGTR1
Angiotensin Amide SCHEMBL21811345 0.79 AGTR2 (0.86) AGTR2AGTR1
SCHEMBL29471347 0.79 AGTR2 (0.69) AGTR2AGTR1FCGRTNPY2RNPY4R
SCHEMBL29393119 0.79 AGTR2 (0.69) AGTR2AGTR1FCGRTNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041325-A1 LIPID-BASED COMPOSITIONS AND METHODS THEREOF UNITED STATES GOVERNMENT 2025-02-06 — — US claimed
WO-2025011541-A1 DRUG MICELLE OF CORE-SHELL-SHELL STRUCTURE HAVING TARGETING FUNCTION AND PREPARATION METHOD THEREFOR 四川大学华西医院 2025-01-16 — — WO claimed
CN-118879605-A Engineering bacillus clausii extracellular vesicles, drug delivery carrier, preparation method and application thereof 上海海洋大学 2024-11-01 — — CN claimed
CN-118236515-A Preparation method and application of black phosphorus nano-sheet drug-loading system 中国医学科学院药物研究所 2024-06-25 — — CN claimed
CN-116570734-B Core-shell structured drug micelle with targeting function and preparation method thereof 四川大学华西医院 2023-10-13 — — CN claimed
CN-116570734-A Core-shell structured drug micelle with targeting function and preparation method thereof 四川大学华西医院 2023-08-11 — — CN claimed
WO-2023107574-A2 LIPID-BASED COMPOSITIONS AND METHODS THEREOF THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) 2023-06-15 — — WO claimed
EP-3267986-B1 PDE5 INHIBITORS FOR USE IN REDUCING RENAL CYST SIZE AND/OR PREVENTING RENAL CYST GROWTH UNIV INDIANA RES & TECH CORP (US) 2022-09-14 — — EP claimed
US-20260137696-A1 Compositions Comprising an Inhibitor of Galectin-3 UNIVERSITY OF LIVERPOOL (GB) 2026-05-21 — — US disclosed
EP-4739296-A1 COMPOSITIONS COMPRISING AN INHIBITOR OF GALECTIN-3 University of Liverpool (GB) 2026-05-13 — — EP disclosed
EP-4739319-A1 COMPOSITIONS COMPRISING AN INHIBITOR OF GALECTIN-3 University of Liverpool (GB) 2026-05-13 — — EP disclosed
US-20260034249-A1 COMPOSITIONS AND METHODS FOR MODIFYING FERTILITY THE BROAD INSTITUTE, INC. (US) 2026-02-05 — — US disclosed
US-20250325686-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM UNIV CORNELL (US) 2025-10-23 — — US disclosed
CN-120549887-A PEG@PLGA@mir-181d nanoparticle based on G3-C12 peptide modification and preparation method and application thereof 右江民族医学院附属医院 2025-08-29 — — CN disclosed
US-11571481-B2 Peptide-linked drug delivery system CORNELL UNIVERSITY (US) 2023-02-07 — — US disclosed
EP-3267986-B1 PDE5 INHIBITORS FOR USE IN REDUCING RENAL CYST SIZE AND/OR PREVENTING RENAL CYST GROWTH UNIV INDIANA RES & TECH CORP (US) 2022-09-14 — — EP disclosed
US-20220251153-A1 PEPTIDES FOR THE TREATMENT OF RENAL DISORDERS UGH PHARMA, INC. (PA) 2022-08-11 — — US disclosed
EP-4021480-A1 PEPTIDES FOR THE TREATMENT OF RENAL DISORDERS The George Washington University (US) 2022-07-06 — — EP disclosed
WO-2022140289-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM CORNELL UNIVERSITY (US) 2022-06-30 — — WO disclosed
US-20220193248-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM CORNELL UNIVERSITY 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325686-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM GLS, AGBL2, ATP6V1B1 AGTR2 128/4885AGTR1 148/4885FCGRT 93/4885
US-20260034249-A1 COMPOSITIONS AND METHODS FOR MODIFYING FERTILITY PGRMC2, TAGLN2, PGRMC1 AGTR2 4237/4885AGTR1 4571/4885FCGRT 1948/4885
US-20220193248-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM GLS, AGBL2, ATP6V1B1 AGTR2 128/4885AGTR1 148/4885FCGRT 93/4885
US-11571481-B2 Peptide-linked drug delivery system GLS, AGBL2, ATP6V1B1 AGTR2 128/4885AGTR1 148/4885FCGRT 93/4885
US-20260137696-A1 Compositions Comprising an Inhibitor of Galectin-3 LGALS3, LGALS1, LGALS2 AGTR2 711/4885AGTR1 795/4885FCGRT 3985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.