Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29635313 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29541179 | 0.93 | ALDH1A1 (0.33) | ALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29635310 | 0.92 | ALDH1A1 (0.31) | ALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29540982 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL29540980 | 0.87 | ALDH1A1 (0.33) | ALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29540788 | 0.86 | KIF11 (0.32) | ALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29541614 | 0.84 | KIF11 (0.32) | — | |
| Hydrochloric Acid SCHEMBL30483485 | 0.76 | ALDH1A1 (0.31) | ALDH1A1HPGDRAB9A | |
| SCHEMBL30483482 | 0.75 | RAB9A (0.34) | ALDH1A1HPGDRAB9A | |
| SCHEMBL30483475 | 0.74 | RAB9A (0.32) | ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2022-03-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | OPRM1, SIGMAR1, AP2S1 | ALDH1A1 4096/4885HPGD 2972/4885RAB9A 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.