Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561065 | 0.86 | LMNA (0.45) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL28316038 | 0.84 | LMNA (0.43) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL2967165 | 0.82 | LMNA (0.45) | EGLN1KDM2AFOLH1LMNAALKBH5 | |
| SCHEMBL4610266 | 0.81 | THRB (0.36) | LMNAPGK1PGK2ALDH1A1PEPD | |
| SCHEMBL29165564 | 0.80 | LMNA (0.39) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL285627 | 0.77 | CA4 (0.48) | LMNAPGK1PGK2PEPDPGD | |
| Succinic Acid SCHEMBL29758477 | 0.77 | LMNA (0.56) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL6854426 | 0.77 | LMNA (0.56) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL321511 | 0.77 | LMNA (0.56) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL19478236 | 0.77 | LMNA (0.56) | EGLN1KDM6BKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772270-B2 | Imino acid derivatives as inhibitors of matrix metalloproteinases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-20060252752-A1 | Octahydrocyclopenta[b]pyrrole-sulfonamide-2-carboxylic acid derivatives; reduced side effects | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-11-09 | — | — | US | disclosed |
| US-20050004166-A1 | Imino acid derivatives as inhibitors of matrix metalloproteinases | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004166-A1 | Imino acid derivatives as inhibitors of matrix metalloproteinases | MMP9, MMP1, MMP25 | EGLN1 697/4885KDM6B 2332/4885KDM5C 1466/4885 |
| US-20060252752-A1 | Octahydrocyclopenta[b]pyrrole-sulfonamide-2-carboxylic acid derivatives; reduced side effects | SULT2A1, ADCYAP1R1, SULT1A1 | EGLN1 2023/4885KDM6B 3164/4885KDM5C 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.