SCHEMBL296753

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL296754	0.90	HDAC3 (0.49)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL281590	0.85	RAB9A (0.59)	MAPK1ALDH1A1RXFP1NPC1LMNA
	SCHEMBL29029431	0.84	HDAC3 (0.56)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL3892771	0.82	ALDH1A1 (0.52)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL2481722	0.82	HDAC3 (0.47)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL5894005	0.82	CA2 (0.52)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL999347	0.82	KMT2A (0.61)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL6470532	0.81	HTT (0.58)	FAAHALDH1A1NPC1LMNAMAPT
	SCHEMBL29991055	0.81	NPC1 (0.55)	ALDH1A1RXFP1NPC1LMNAMAPT
	SCHEMBL18904875	0.81	HDAC3 (0.46)	HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.