Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.63 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.53 |
| ▸ | FABP3 | P05413 | 7/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402678 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6053545 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL30930281 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Pimelic Acid SCHEMBL6756717 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Sebacic Acid SCHEMBL306520 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL20577558 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Azelaic Acid SCHEMBL852024 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11046980 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Octanedioate SCHEMBL188028 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8325989 | 1.00 | CA1 (0.63) | CA1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718076-B1 | Biodegradable tensioning film and fabrication processes for making same | CORTEC CORPORATION (US) | 2023-08-08 | — | — | US | claimed |
| US-11718076-B1 | Biodegradable tensioning film and fabrication processes for making same | CORTEC CORPORATION (US) | 2023-08-08 | — | — | US | disclosed |
| WO-2022138931-A1 | COMPOUND, CORROSION INHIBITOR, AND LUBRICANT COMPOSITION | 出光興産株式会社 | 2022-06-30 | — | — | WO | disclosed |