Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587229 | 0.67 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2HIF1A | |
| SCHEMBL62806 | 0.65 | PTGES (0.40) | ALDH1A1MAPTSMN1; SMN2HSD17B10ELANE | |
| SCHEMBL7330865 | 0.65 | MAOA (0.33) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL2514183 | 0.64 | ELANE (0.32) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL24891350 | 0.59 | ELANE (0.61) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL868661 | 0.59 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL30305755 | 0.59 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL30966887 | 0.57 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL29391754 | 0.57 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN | |
| SCHEMBL257 | 0.57 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2HSD17B10GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332455-B2 | α,β-unsaturated amide compound | KYOWA KIRIN CO., LTD. (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20210380551-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-20210155612-A1 | Alpha,Beta-UNSATURATED AMIDE COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2021-05-27 | — | — | US | disclosed |
| US-10787428-B2 | α,β-unsaturated amide compound | KYOWA KIRIN CO., LTD. (JP) | 2020-09-29 | — | — | US | disclosed |
| EP-3712129-A1 | ALPHA, BETA-UNSATURATED AMIDE COMPOUND | Kyowa Kirin Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |
| CN-110770211-A | α unsaturated amide compound | 协和麒麟株式会社 | 2020-02-07 | — | — | CN | disclosed |
| US-20190010136-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3401309-A1 | a, ß UNSATURATED AMIDE COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-11-14 | — | — | EP | disclosed |
| US-8709377-B2 | Molecular hydrogen stores and hydrogen transfer reagents for hydrogenation reactions | UNIVERSITAT HEIDELBERG (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20100172825-A1 | Molecular Hydrogen Stores and Hydrogen Transfer Reagents for Hydrogenation Reactions | UNIVERSITAT HEIDELBERG (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155612-A1 | Alpha,Beta-UNSATURATED AMIDE COMPOUND | NR1H2, NR1H3, RXRA | ALDH1A1 675/4885MAPT 4512/4885SMN1; SMN2 796/4885 |
| US-20100172825-A1 | Molecular Hydrogen Stores and Hydrogen Transfer Reagents for Hydrogenation Reactions | HVCN1, HHAT, HDHD5 | ALDH1A1 2985/4885MAPT 1703/4885SMN1; SMN2 4681/4885 |
| US-10787428-B2 | α,β-unsaturated amide compound | NR1H2, NCOA1, NR0B1 | ALDH1A1 816/4885MAPT 4675/4885SMN1; SMN2 864/4885 |
| US-20210380551-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | NR1H2, NR1H3, NCOA1 | ALDH1A1 754/4885MAPT 4605/4885SMN1; SMN2 845/4885 |
| US-11332455-B2 | α,β-unsaturated amide compound | NR1H2, NCOA1, NR0B1 | ALDH1A1 816/4885MAPT 4675/4885SMN1; SMN2 864/4885 |
| US-20190010136-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | NR1H2, NR1H3, NCOA1 | ALDH1A1 754/4885MAPT 4605/4885SMN1; SMN2 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.