Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | USP19 | O94966 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29465057 | 0.88 | TSHR (0.61) | L3MBTL3L3MBTL1TSHRRECQLRAB9A | |
| SCHEMBL29465023 | 0.85 | SIGMAR1 (0.51) | L3MBTL3L3MBTL1TSHRRECQLUSP19 | |
| SCHEMBL19815809 | 0.84 | L3MBTL1 (0.55) | L3MBTL1TSHRRECQLRAB9ACHEK1 | |
| SCHEMBL19816945 | 0.84 | ALDH1A1 (0.52) | TSHRRECQLRAB9ALMNA | |
| SCHEMBL29857137 | 0.79 | HRH4 (0.49) | L3MBTL3L3MBTL1TSHRRECQLUSP19 | |
| SCHEMBL19817301 | 0.75 | PRKAB2 (0.54) | PRKAA1DYRK1A | |
| SCHEMBL29857542 | 0.72 | CA1 (0.41) | — | |
| SCHEMBL8708978 | 0.72 | GFER (0.67) | ATMAVPR1ARAB9AGFERLMNA | |
| SCHEMBL21891709 | 0.72 | CPB1 (0.68) | L3MBTL3L3MBTL1TSHRRECQLGRM5 | |
| SCHEMBL19815338 | 0.72 | BCAT2 (0.55) | ATMRAB9ACDC7PLK4CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790146-B | Pharmaceutical compounds | 阿尔麦克探索有限公司 | 2022-08-23 | — | — | CN | disclosed |