SCHEMBL29906308

SCHEMBL29906308

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TERT O14746 1/20 0.43
DPP7 Q9UHL4 1/20 0.40
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
PRCP P42785 2/20 0.38
REN P00797 1/20 0.38
PSMB5 P28074 3/20 0.38
CAPN1 P07384 2/20 0.37
CAPN9 O14815 1/20 0.37
CTSB P07858 1/20 0.37
MAPK1 P28482 1/20 0.37
MAPT P10636 1/20 0.37
CTSC P53634 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30099495 0.95 MEN1 (0.41) MEN1KMT2ATERTDPP7ALDH1A1
SCHEMBL30099556 0.92 TERT (0.42) MEN1KMT2ATERTDPP7ALDH1A1
SCHEMBL30487458 0.91 TERT (0.51) MEN1KMT2ATERTDPP7ALDH1A1
SCHEMBL29570472 0.91 TERT (0.51) MEN1KMT2ATERTDPP7ALDH1A1
SCHEMBL29388130 0.90 TERT (0.41) MEN1KMT2ATERTDPP7ALDH1A1
SCHEMBL10789594 0.89 TERT (0.40) MEN1KMT2ATERTDPP7PRCP
SCHEMBL10789606 0.89 TERT (0.40) MEN1KMT2ATERTDPP7PRCP
SCHEMBL5287122 0.88 TERT (0.42) MEN1KMT2ATERTDPP7PRCP
SCHEMBL12601584 0.88 TERT (0.42) MEN1KMT2ATERTDPP7PRCP
SCHEMBL1369569 0.88 DPP7 (0.43) MEN1KMT2ATERTDPP7PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250123280-A1 LABEL-FREE DETECTION OF PROTEASE ACTIVITY UNIV OREGON HEALTH & SCIENCE (US) 2025-04-17 US claimed
US-20240287509-A1 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (CN) 2024-08-29 US claimed
WO-2023003984-A2 LABEL-FREE DETECTION OF PROTEASE ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-01-26 WO claimed
EP-4056168-A9 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF Shanghai Jiaotong University School of Medicine (CN) 2022-11-23 EP claimed
EP-4056168-A1 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF Shanghai Jiaotong University School of Medicine (CN) 2022-09-14 EP claimed
US-12618835-B2 Multiplex microelectrode array for detection of proteases as biomarkers KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2026-05-05 US disclosed
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists BAYER AKTIENGESELLSCHAFT (DE) 2025-08-26 US disclosed
US-12371691-B2 Nano complex for targeted repairing of neurovascular lesion, and preparation and use thereof SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (CN) 2025-07-29 US disclosed
CN-115720578-B And tricyclic derivatives, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2025-06-13 CN disclosed
US-20250123280-A1 LABEL-FREE DETECTION OF PROTEASE ACTIVITY UNIV OREGON HEALTH & SCIENCE (US) 2025-04-17 US disclosed
US-20240287509-A1 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (CN) 2024-08-29 US disclosed
CN-113735825-B 1,2,3, 6-Tetrahydropyridine compound and preparation method and application thereof 成都康弘药业集团股份有限公司 2024-08-27 CN disclosed
CN-115720578-A Tricyclic derivative, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2023-02-28 CN disclosed
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
US-20230027985-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
WO-2023003984-A2 LABEL-FREE DETECTION OF PROTEASE ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-01-26 WO disclosed
US-20220412975-A1 CHARACTERIZING MODULATORS OF ADAMTS-7 AND ADAMTS-12 BAYER AKTIENGESELLSCHAFT (DE) 2022-12-29 US disclosed
EP-4056168-A9 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF Shanghai Jiaotong University School of Medicine (CN) 2022-11-23 EP disclosed
US-20220349880-A1 MULTIPLEX MICROELECTRODE ARRAY FOR DETECTION OF PROTEASES AS BIOMARKERS UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-11-03 US disclosed
EP-4056168-A1 NANO COMPLEX FOR TARGETED REPAIRING OF NEUROVASCULAR LESION, AND PREPARATION AND USE THEREOF Shanghai Jiaotong University School of Medicine (CN) 2022-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618835-B2 Multiplex microelectrode array for detection of proteases as biomarkers APAF1, ADAM33, UCHL1 MEN1 4195/4885KMT2A 3531/4885TERT 2743/4885
US-20230027985-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAMTS1 MEN1 2636/4885KMT2A 3100/4885TERT 4570/4885
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists ADAMTS7, MMP7, ADAM17 MEN1 2481/4885KMT2A 3535/4885TERT 4278/4885
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAM17 MEN1 2481/4885KMT2A 3535/4885TERT 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.