Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.59 |
| ▸ | GHSR | Q92847 | 2/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | IL23R | Q5VWK5 | 11/20 | 0.56 |
| ▸ | GLP1R | P43220 | 4/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29641022 | 0.97 | IL23R (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL30309224 | 0.92 | C5AR1 (0.66) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL29884974 | 0.91 | C5AR1 (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL29641153 | 0.91 | C5AR1 (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL29540499 | 0.91 | C5AR1 (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL29461998 | 0.91 | C5AR1 (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL29540716 | 0.91 | C5AR1 (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL31680254 | 0.91 | C5AR1 (0.58) | C5AR1GHSRNPY2RIL23RGLP1R | |
| SCHEMBL30097937 | 0.90 | IL23R (0.63) | GHSRNPY2RIL23R | |
| SCHEMBL31680253 | 0.90 | C5AR1 (0.61) | C5AR1GHSRNPY2RTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319152-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING | STEALTH BIOTHERAPEUTICS INC. (US) | 2025-10-16 | — | — | US | disclosed |
| US-20250263433-A1 | METHODS FOR REDUCING CD36 EXPRESSION | CORNELL RESEARCH FOUNDATION, INC. (US) | 2025-08-21 | — | — | US | disclosed |
| EP-4596049-A2 | PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION | Stealth BioTherapeutics Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| EP-4302829-B1 | PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION | STEALTH BIOTHERAPEUTICS INC (US) | 2025-05-21 | — | — | EP | disclosed |
| EP-3603658-B1 | PEPTIDE FOR USE IN THE TREATMENT OF HEART FAILURE RESULTING FROM HYPERTROPHIC CARDIOMYOPATHY | UNIV CORNELL (US) | 2025-01-08 | — | — | EP | disclosed |
| US-12102659-B2 | Methods for the prevention or treatment of heart failure | CORNELL UNIVERSITY (US) | 2024-10-01 | — | — | US | disclosed |
| US-11998585-B2 | Methods and compositions for increasing the dose of a chemotherapeutic agent | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-11944662-B2 | Methods and compositions for preventing or treating ophthalmic conditions | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-04-02 | — | — | US | disclosed |
| EP-4302829-A2 | PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION | Stealth BioTherapeutics Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| US-20230381264-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-11-30 | — | — | US | disclosed |
| EP-3708178-B1 | PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION | STEALTH BIOTHERAPEUTICS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| US-20230293624-A1 | METHODS FOR PREVENTING OR TREATING MITOCHONDRIAL PERMEABILITY TRANSITION | CORNELL RESEARCH FOUNDATION, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230285499-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE | CORNELL UNIVERSITY (US) | 2023-09-14 | — | — | US | disclosed |
| US-20220296672-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285499-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE | TNNI3, FABP3, TNNC1 | C5AR1 1061/4885GHSR 918/4885NPY2R 696/4885 |
| US-11944662-B2 | Methods and compositions for preventing or treating ophthalmic conditions | CRYAA, CRYAB, IAPP | C5AR1 264/4885GHSR 619/4885NPY2R 198/4885 |
| US-20220296672-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY | NGF, GAP43, PRPH | C5AR1 122/4885GHSR 1950/4885NPY2R 395/4885 |
| US-12102659-B2 | Methods for the prevention or treatment of heart failure | TNNI3, FABP3, TNNC1 | C5AR1 1061/4885GHSR 918/4885NPY2R 696/4885 |
| US-11998585-B2 | Methods and compositions for increasing the dose of a chemotherapeutic agent | OPRL1, TSG101, NGF | C5AR1 46/4885GHSR 2459/4885NPY2R 914/4885 |
| US-20250319152-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING | ARG2, TNNT2, MYLK2 | C5AR1 3385/4885GHSR 1557/4885NPY2R 313/4885 |
| US-20230381264-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS | CRYAA, CRYAB, IAPP | C5AR1 264/4885GHSR 619/4885NPY2R 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.