SCHEMBL29946263

SCHEMBL29946263

CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(=O)N[C@H](C=O)CC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CASP1 P29466 3/20 0.47
▸ CASP3 P42574 3/20 0.47
▸ CASP9 P55211 3/20 0.47
▸ CASP7 P55210 1/20 0.47
▸ CTSK P43235 4/20 0.41
▸ CTSS P25774 1/20 0.41
▸ CASP4 P49662 1/20 0.41
▸ CASP5 P51878 1/20 0.41
▸ CASP6 P55212 1/20 0.41
▸ CASP8 Q14790 1/20 0.41
▸ CASP10 Q92851 1/20 0.41
▸ REN P00797 2/20 0.40
▸ FNTA P49354 1/20 0.39
▸ FNTB P49356 1/20 0.39
▸ BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13194679 0.81 CASP1 (0.50) CASP1CASP3CASP9CASP7CASP4
SCHEMBL4100803 0.81 CASP1 (0.50) CASP1CASP3CASP9CASP7CASP4
SCHEMBL1674857 0.81 CASP1 (0.50) CASP1CASP3CASP9CASP7CASP4
SCHEMBL29310042 0.81 CASP1 (0.50) CASP1CASP3CASP9CASP7CASP4
SCHEMBL10068454 0.81 CASP1 (0.47) CASP1CASP3CASP9CASP7CASP4
SCHEMBL29664642 0.80 CASP1 (0.47) CASP1CASP3CASP9CASP7CASP4
SCHEMBL7470374 0.78 CASP3 (0.45) CASP1CASP3CASP9CASP7CTSK
SCHEMBL23133189 0.77 CASP1 (0.49) CASP1CASP3CASP9CASP7CASP4
SCHEMBL23133187 0.77 CASP1 (0.49) CASP1CASP3CASP9CASP7CASP4
SCHEMBL20257122 0.77 CASP1 (0.49) CASP1CASP3CASP9CASP7CASP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 — — US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 — — US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 — — EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 — — EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 — — US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CASP1 1854/4885CASP3 1797/4885CASP9 1206/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 CASP1 1854/4885CASP3 1797/4885CASP9 1206/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CASP1 1854/4885CASP3 1797/4885CASP9 1206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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