Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 6/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 6/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 6/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 6/20 | 0.38 |
| ▸ | ATP4A | P20648 | 6/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 6/20 | 0.38 |
| ▸ | ATP4B | P51164 | 6/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 6/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 6/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 6/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991803 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1L3MBTL1DYRK1ASMN1; SMN2LMNA | |
| SCHEMBL12819972 | 0.84 | MAPT (0.39) | ALDH1A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL8503292 | 0.83 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1PDCD1CD274DYRK1A | |
| SCHEMBL8469392 | 0.82 | ATP1A1 (0.37) | ALDH1A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL3393106 | 0.82 | ATP1A1 (0.37) | ALDH1A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL30163883 | 0.82 | ATP1A1 (0.37) | ALDH1A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL8088378 | 0.82 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1DYRK1ALMNAPDE4D | |
| SCHEMBL2991691 | 0.82 | IKBKB (0.39) | ALDH1A1L3MBTL1DYRK1AUSP2LMNA | |
| Hydrochloric Acid SCHEMBL2111356 | 0.81 | PDE10A (0.38) | ALDH1A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL13195683 | 0.81 | ATP1A1 (0.39) | ALDH1A1ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159530-A | Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling | 康福治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-8778975-B2 | Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion | Link Geonomics, Inc. (JP) | 2014-07-15 | — | — | US | disclosed |
| CN-103539728-A | Synthesis method of lansoprazole drug intermediate chloromethyl pyridine derivative | ANHUI COSTAR BIO CHEMICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |
| EP-2103608-B1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS INC (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-07-08 | — | — | US | disclosed |
| US-20100113524-A1 | Prodrugs of proton pump inhibitors including the (1h-pyrrol-1-yl)-1h-benzimidazole moiety | ALEVIUM PHARMACEUTICALS, INC. | 2010-05-06 | — | — | US | disclosed |
| EP-2103608-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | Arigen, Pharmaceuticals, Inc. (JP) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008036211-A1 | PRODRUGS OF PROTON PUMP INHIBITORS INCLUDING THE (1H-PYRROL-1-YL)-1H-BENZIMIDAZOLE MOIETY | ALEVIUM PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |
| EP-0475456-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-5045552-A | Pyridine derivatives having anti-ulcerative activity | EISAI CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0127763-B1 | TRICYCLIC ETHERS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0268956-A2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1988-06-01 | — | — | EP | disclosed |
| US-4560693-A | ANTISECRETORY, ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-12-24 | — | — | US | disclosed |
| US-4555518-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0134400-A2 | Fluoroalkoxysubstituted pyridylmethylthio-(or sulfinyl-)benzimidazoles having a secretolytic activity | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| EP-0127763-A1 | Tricyclic ethers, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-12-12 | — | — | EP | disclosed |
| US-4472409-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-18 | — | — | US | disclosed |
| EP-0080602-A1 | Substituted benzimidazoles, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | AHR, ARNT, MTNR1A | ALDH1A1 752/4885L3MBTL1 2260/4885PDCD1 3711/4885 |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | GIPR, PGC, SLC10A2 | ALDH1A1 1629/4885L3MBTL1 4836/4885PDCD1 3052/4885 |
| US-20100113524-A1 | Prodrugs of proton pump inhibitors including the (1h-pyrrol-1-yl)-1h-benzimidazole moiety | ABCB11, ATP6AP1, PAH | ALDH1A1 290/4885L3MBTL1 1994/4885PDCD1 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.