Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955732 | 0.77 | KMO (0.51) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL8296662 | 0.76 | L3MBTL1 (0.60) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL29999740 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL8798927 | 0.72 | MET (0.57) | ALDH1A1HPGDMETKMOMAPT | |
| SCHEMBL14615583 | 0.72 | MAOB (0.39) | ALDH1A1HPGDCA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL9157992 | 0.71 | MET (0.56) | ALDH1A1HPGDMETKMOMAPT | |
| SCHEMBL4413088 | 0.70 | HPGD (0.59) | HPGDMETKMOPOLBSMN1; SMN2 | |
| SCHEMBL4067603 | 0.70 | KMO (0.46) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL14199043 | 0.70 | POLB (0.52) | ALDH1A1HPGDMETKMOMAPT | |
| SCHEMBL30349961 | 0.69 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506539-B1 | Heterocyclic alkylamides, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-05-02 | — | — | EP | disclosed |
| EP-0506539-A1 | Heterocyclic alkylamides, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-09-30 | — | — | EP | disclosed |