Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457488 | 0.82 | HDAC6 (0.65) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL17457487 | 0.82 | HDAC6 (0.65) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL78063 | 0.81 | ALOX15 (0.61) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6887653 | 0.81 | MAPT (0.62) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL301051 | 0.81 | MAPT (0.62) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL20194015 | 0.79 | PTPN1 (0.67) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL17472006 | 0.79 | PTPN1 (0.67) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL14130013 | 0.79 | MAPT (0.68) | TRPA1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL168297 | 0.77 | TRPA1 (1.00) | TRPA1MAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL20307199 | 0.77 | TRPA1 (1.00) | TRPA1MAPTRAB9AL3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714560-B2 | Protected scale inhibitors and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-25 | — | — | US | claimed |
| US-9493469-B2 | Piperidine inhibitors of Janus kinase 3 | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | claimed |
| EP-2727915-A1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | Concert Pharmaceuticals Inc. (US) | 2014-05-07 | — | — | EP | claimed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-4149949-A1 | BORONIC ACID DERIVATIVES AND SYNTHESIS, POLYMORPHIC FORMS, AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA, INC. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-11237156-B2 | Method and composition for detection of peptide cyclization using protein tags | Roche Sequencing Solutions, Inc. (US) | 2022-02-01 | — | — | US | disclosed |
| US-11208390-B2 | Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions | THE GENERAL HOSPITAL CORPORATION (US) | 2021-12-28 | — | — | US | disclosed |
| WO-2021226114-A1 | BORONIC ACID DERIVATIVES AND SYNTHESIS, POLYMORPHIC FORMS, AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-3497446-B1 | METHOD AND COMPOSITION FOR DETECTION OF PEPTIDE CYCLIZATION USING PROTEIN TAGS | HOFFMANN LA ROCHE (CH) | 2021-04-28 | — | — | EP | disclosed |
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | SOLVIAS AG (CH) | 2004-01-15 | — | — | US | disclosed |
| EP-1378500-A1 | Diastereoselective hydrogenation of beta-hydroxy ketones | Solvias AG (CH) | 2004-01-07 | — | — | EP | disclosed |
| EP-1378501-A1 | Diastereoselective hydrogenation of beta-hydroxyketones | Solvias AG (CH) | 2004-01-07 | — | — | EP | disclosed |
| WO-2003092581-A2 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | HK PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| US-20030119021-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-06-26 | — | — | US | disclosed |
| WO-2003044011-A1 | PYRROLE SYNTHESIS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |
| WO-2003004456-A1 | PROCESS FOR THE PREPARATION OF 7-AMINO SYN 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES VIA 6-CYANO SYN 3,5-DIHYDROXY HEXANOIC ACID DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-01-16 | — | — | WO | disclosed |
| WO-2003004455-A2 | PROCESS FOR THE PREPARATION OF 7-AMINO SYN 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES, INTERMEDIATES THEREOF AND METHODS FOR THEIR PREPARATION | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-01-16 | — | — | WO | disclosed |
| WO-2003004450-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF STATIN DERIVATIVES ESPECIALLY 7-AMINO 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES, AND INTERMEDIATES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208390-B2 | Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions | TIE1, TTL, EPHA2 | TRPA1 4728/4885MAPT 925/4885RAB9A 4257/4885 |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | TRPA1 4586/4885MAPT 4170/4885RAB9A 3139/4885 |
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | HK1, HSD17B7, GRIK1 | TRPA1 2042/4885MAPT 3335/4885RAB9A 3034/4885 |
| US-11237156-B2 | Method and composition for detection of peptide cyclization using protein tags | CACYBP, VIP, PTMS | TRPA1 4296/4885MAPT 4285/4885RAB9A 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.