Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114163 | 0.87 | ALDH1A1 (0.46) | ALDH1A1ACLYMAPK1TAS2R14LMNA | |
| SCHEMBL24880072 | 0.77 | WDR5 (0.39) | ACLYMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL30113958 | 0.77 | WDR5 (0.39) | ACLYMAPTGAASMN1; SMN2LMNA | |
| SCHEMBL30114488 | 0.76 | BMP1 (0.60) | ALDH1A1MAPTTAS2R14LMNAKMT2A | |
| SCHEMBL30194803 | 0.72 | TNNI3K (0.45) | ALDH1A1MAPTSMN1; SMN2TGFBR1 | |
| SCHEMBL30114634 | 0.72 | BMP1 (0.50) | ALDH1A1MAPTKMT2ABMP1 | |
| SCHEMBL30014545 | 0.71 | APLNR (0.51) | ACLYSMN1; SMN2TAS2R14LMNAKMT2A | |
| SCHEMBL29966020 | 0.70 | LMNA (0.63) | ALDH1A1MAPTGAASMN1; SMN2MAPK1 | |
| SCHEMBL6958238 | 0.69 | TAS2R14 (0.64) | ALDH1A1ACLYTAS2R14KMT2A | |
| SCHEMBL4012164 | 0.69 | TAS2R14 (0.53) | ALDH1A1ACLYTAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |