SCHEMBL301235

SCHEMBL301235

CC(C)(C)c1cccc(P)c1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.48
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KIF11 P52732 1/20 0.35
ALOX12 P18054 1/20 0.34
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL766664 0.98 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL380248 0.98 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TSHR
Hydrochloric Acid SCHEMBL28640990 0.98 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TSHR
Hydrochloric Acid SCHEMBL380015 0.95 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL28360323 0.91 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL28997090 0.91 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1304225 0.91 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL304569 0.84 CA2 (0.57) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL28153792 0.82 CA2 (0.38) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL5910979 0.80 CA2 (0.32) CA2ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946732-B Solid removing agent and method for deeply removing solid content in catalytic cracking slurry oil 中国石油化工股份有限公司 2026-05-19 CN claimed
US-12624005-B2 Synthesis of 4-amino-6-(heterocyclic)picolinates CORTEVA AGRISCIENCE LLC (US) 2026-05-12 US claimed
CN-122010861-A Buronate clamp Process for the preparation of a medicament 杭州科巢生物科技有限公司 2026-05-12 CN claimed
EP-4574808-A1 PROCESS FOR THE HYDROFORMYLATION OF AN ALIPHATIC ALKENE Université de Strasbourg (FR) 2025-06-25 EP claimed
CN-118047748-A Preparation method of phosphorus-catalyzed vinylene carbonate 深圳有为技术控股集团有限公司 2024-05-17 CN claimed
CN-114989000-B Process for preparing unsaturated carboxylic acids by carbonylation of allyl alcohol and its acylated products 巴斯夫欧洲公司 2024-05-10 CN claimed
CN-117946732-A Solid removing agent and method for deeply removing solid content in catalytic cracking slurry oil 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117285454-A Synthesis method of indole derivative and benzodipyrrole derivative 南京邮电大学 2023-12-26 CN claimed
US-20230357155-A1 IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES CORTEVA AGRISCIENCE LLC (US) 2023-11-09 US claimed
WO-2023125373-A1 METHOD FOR PREPARING RUXOLITINIB AND INTERMEDIATE THEREOF 江苏威凯尔医药科技有限公司 2023-07-06 WO claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
WO-2005042147-A2 SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS PROMERUS, LLC (US) 2005-05-12 WO claimed
US-6818368-B2 AN ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER INCLUDES CHARGE GENERATING AND CHARGE TRANSFER MATERIALS, CHARGE TRANSFER MATERIAL CONTAINS A TRIARYLAMINE COMPOUND FORMED FROM AN AMINE AND AN ARYLHALIDE WITH PHOSPHINE COMOUND CATALYST CANON KABUSHIKI KAISHA (JP) 2004-11-16 US claimed
US-20030229240-A1 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2003-12-11 US claimed
US-20030149272-A1 Method for preparing a polyaromatic compound RHODIA CHIMIE (FR) 2003-08-07 US claimed
JP-2003522744-A 2003-07-29 JP claimed
EP-1255715-A1 METHOD FOR PREPARING A POLYAROMATIC COMPOUND RHODIA CHIMIE (FR) 2002-11-13 EP claimed
WO-2001058834-A1 METHOD FOR PREPARING A POLYAROMATIC COMPOUND RHODIA CHIMIE (FR) 2001-08-16 WO claimed
EP-0351336-B1 PROCESS FOR THE PREPARATION OF HYDROXYBENZALDEHYDES BY HYDROCARBONYLATION RHONE-POULENC CHIMIE (FR) 1992-10-28 EP claimed
US-4933497-A Preparation of hydroxybenzaldehydes by hydrocarbonylation of halophenols RHONE-POULENC CHIMIE (FR) 1990-06-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357155-A1 IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES APC, PPOX, ALAD CA2 2883/4885GABRA1 2743/4885GABRB2 1958/4885
US-12624005-B2 Synthesis of 4-amino-6-(heterocyclic)picolinates CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS CA2 41/4885GABRA1 2155/4885GABRB2 2077/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP CA2 223/4885GABRA1 4394/4885GABRB2 4249/4885
US-20030149272-A1 Method for preparing a polyaromatic compound PCNA, PAH, AOC1 CA2 1294/4885GABRA1 3958/4885GABRB2 4370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.