Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313624 | 0.77 | KMT2A (0.57) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10826057 | 0.73 | SLC2A1 (0.46) | NPC1RAB9AALDH1A1PPARGC5AR1 | |
| SCHEMBL18313460 | 0.72 | NPC1 (0.46) | NPC1RAB9AGAAC5AR1KMT2A | |
| SCHEMBL16929939 | 0.72 | SIGMAR1 (0.45) | — | |
| SCHEMBL16930062 | 0.71 | LDHA (0.51) | ALDH1A1PPARGKMT2A | |
| SCHEMBL16260128 | 0.68 | SLC6A4 (0.54) | NPC1RAB9ADPP4CYP1A2CYP3A4 | |
| SCHEMBL23640070 | 0.67 | TAAR1 (0.55) | MAPTMAOA | |
| SCHEMBL26851116 | 0.67 | TAAR1 (0.55) | MAPTMAOA | |
| SCHEMBL11833131 | 0.67 | TAAR1 (0.55) | MAPTMAOA | |
| SCHEMBL17481408 | 0.67 | SLC2A1 (0.53) | RAB9AGAALMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560352-B2 | P62-ZZ small molecule modulators | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560352-B2 | P62-ZZ small molecule modulators | ADRM1, SQSTM1, NCOR1 | NPC1 564/4885RAB9A 1676/4885GAA 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.