SCHEMBL3016490

SCHEMBL3016490

c1ccc(-c2cc3cc(CCN4CCCC4)cc(NC4CCCC4)c3[nH]2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 4/20 0.41
HRH3 Q9Y5N1 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 3/20 0.40
VCP P55072 1/20 0.40
GAA P10253 1/20 0.40
SLC6A3 Q01959 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP3A4 P08684 2/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ADORA2A P29274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3008784 0.85 ADORA2A (0.41) NPY5RALDH1A1VCPMEN1ALOX15
SCHEMBL25014985 0.85 ADORA2A (0.41) NPY5RALOX15ADORA2AADORA1KCNH2
SCHEMBL24988637 0.83 ADORA2A (0.40) NPY5RVCPADORA2AADORA1KCNH2
SCHEMBL3008877 0.82 ADORA2A (0.42) NPY5RALDH1A1GAAKDM4EMEN1
SCHEMBL29205640 0.82 ADORA2A (0.39) NPY5RVCPGAAKDM4EMAPT
SCHEMBL25014500 0.82 ADORA2A (0.41) NPY5RALOX15ADORA2AADORA1KCNH2
SCHEMBL24988862 0.82 ADORA2A (0.39) NPY5RALDH1A1HSD17B10KDM4ECYP3A4
SCHEMBL25014577 0.81 ADORA2A (0.41) NPY5RVCPALOX15ADORA2AADORA1
SCHEMBL24988638 0.81 MPL (0.39) NPY5RVCPADORA2AADORA1KCNH2
SCHEMBL3011196 0.81 KDM4E (0.42) NPY5RALDH1A1VCPKDM4EADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-07-03 US claimed
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-03-13 US claimed
EP-4470541-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MitoImmune Therapeutics Inc. (KR) 2024-12-04 EP claimed
US-20240374646-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME MITOIMMUNE THERAPEUTICS INC. (KR) 2024-11-14 US claimed
WO-2024191106-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF EPILEPSY 주식회사 미토이뮨테라퓨틱스 2024-09-19 WO claimed
US-20240269145-A1 USE OF INDOLE COMPOUND AS INHIBITORS OF FERROPTOSIS MITOIMMUNE THERAPEUTICS INC. (KR) 2024-08-15 US claimed
EP-4382106-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME MitoImmune Therapeutics Inc. (KR) 2024-06-12 EP claimed
WO-2023182840-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-09-28 WO claimed
WO-2023146341-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-08-03 WO claimed
WO-2022220517-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME 주식회사 미토이뮨테라퓨틱스 2022-10-20 WO claimed
EP-2178870-B1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG CHEMICAL LTD (KR) 2018-09-19 EP claimed
US-20150038500-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS CATHOLIC UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-02-05 US claimed
CN-101784543-B Indole and indazole compounds as inhibitors of cellular necrosis LG LIFE SCIENCES LTD 2013-10-16 CN claimed
US-8436038-B2 Indole and indazole compounds as an inhibitor of cellular necrosis LG LIFE SCIENCES LTD. (KR) 2013-05-07 US claimed
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD (KR) 2010-08-05 US claimed
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-07-03 US disclosed
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-03-13 US disclosed
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD (KR) 2010-08-05 US disclosed
EP-2178870-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG Life Sciences Ltd. (KR) 2010-04-28 EP disclosed
WO-2009025478-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD. (KR) 2009-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374646-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME TFAM, FIS1, AIFM1 NPY5R 4501/4885HRH3 4809/4885ALDH1A1 160/4885
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF CYP19A1, NR5A1, CYP11A1 NPY5R 2777/4885HRH3 4247/4885ALDH1A1 1154/4885
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF ZC3HAV1, ZC3HAV1L, SARS1 NPY5R 4482/4885HRH3 2404/4885ALDH1A1 1088/4885
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS IDO1, IDO2, NFATC1 NPY5R 2110/4885HRH3 637/4885ALDH1A1 1971/4885
US-20150038500-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS AQP1, EYA3, SF1 NPY5R 3163/4885HRH3 1081/4885ALDH1A1 627/4885
US-20240269145-A1 USE OF INDOLE COMPOUND AS INHIBITORS OF FERROPTOSIS AIFM2, FECH, SLC40A1 NPY5R 2213/4885HRH3 2128/4885ALDH1A1 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.