Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11843372 | 0.93 | USP2 (0.59) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL2806428 | 0.91 | TSHR (0.64) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL27945046 | 0.89 | USP2 (0.56) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL13186036 | 0.88 | ESR2 (0.60) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL14657242 | 0.86 | USP2 (0.53) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL27463215 | 0.85 | USP2 (0.56) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL4089889 | 0.85 | TSHR (0.56) | USP2TSHRTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL13687812 | 0.83 | KMT2A (0.50) | USP2TSHRTP53ALDH1A1POLB | |
| SCHEMBL13699366 | 0.83 | ALDH1A1 (0.60) | USP2ALDH1A1SRD5A2CA1CA2 | |
| SCHEMBL2744381 | 0.83 | USP2 (0.50) | USP2TSHRTP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 800 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102651-A1 | ADHESIVE COMPOSITION AND LAMINATE WITH SAME | ARKEMA FRANCE (FR) | 2026-05-21 | — | — | WO | claimed |
| CN-115362142-A | Use of substituted cinnamates as stabilizers for organic materials, stabilized organic materials, methods of stabilizing organic materials, and specific cinnamates | 弗劳恩霍夫应用研究促进协会 | 2022-11-18 | — | — | CN | claimed |
| CN-113348205-A | Method for stabilizing halogen-free thermoplastic recyclates, plastic composition, stabilizer composition and use of stabilizer composition | 弗劳恩霍夫应用研究促进协会 | 2021-09-03 | — | — | CN | claimed |
| CN-111448250-A | Method for stabilizing halogen-free thermoplastic recyclates, stabilized plastics composition and moulding compound and moulded parts produced therefrom | 弗劳恩霍夫应用研究促进协会 | 2020-07-24 | — | — | CN | claimed |
| US-4460649-A | MULTISEGMENT POLYAMIDE AND POLYESTER | KOLON INDUSTRIES INC. (KR) | 1984-07-17 | — | — | US | claimed |
| WO-2026102651-A1 | ADHESIVE COMPOSITION AND LAMINATE WITH SAME | ARKEMA FRANCE (FR) | 2026-05-21 | — | — | WO | disclosed |
| US-20260137174-A1 | SOLE STRUCTURES, AND ARTICLES OF FOOTWEAR FORMED THEREFROM | NIKE, INC. (US) | 2026-05-21 | — | — | US | disclosed |
| CN-114449914-B | Sole structure including composite elements and articles of footwear formed therefrom | 耐克创新有限合伙公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122004563-A | Article having structural color and method of making a structural colored article | 耐克创新有限合伙公司 | 2026-05-12 | — | — | CN | disclosed |
| US-20260034763-A1 | COMPOSITE TEXTILES AND ARTICLES OF FOOTWEAR FORMED THEREFROM | NIKE INC (US) | 2026-02-05 | — | — | US | disclosed |
| US-12532945-B2 | Sole structures, and articles of footwear formed therefrom | NIKE, INC. (US) | 2026-01-27 | — | — | US | disclosed |
| US-12528939-B2 | Filled polymeric resin materials and methods of making | NIKE, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-4179578-A | Para-phenyl stilbene derivatives | SANDOZ LTD. (CH) | 1979-12-18 | — | — | US | disclosed |
| US-4165556-A | BONDING SERIES OF POLYMERS, SWELLING, SHRINKAGE, IMPREGNATION, COAGULATING | KANEBO, LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4073988-A | POROMERIC MATERIALS | KANEBO, LTD. (JA) | 1978-02-14 | — | — | US | disclosed |
| US-4032558-A | PARA-PHENYL STILBENE DERIVATIVES | SANDOZ LTD. (CH) | 1977-06-28 | — | — | US | disclosed |
| US-4008262-A | DISPERSE DYE INTERMEDIATE | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-3966865-A | POLYAMIDES, POLYOLEFINS, POLYESTERS, POLYACRYLONITRILE, BENZYL ALCOHOL, PHENYLETHYL ALCOHOL | KANEBO, LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
| US-3954830-A | Yellow methine dyes for hydrophobic textile material | AMERICAN ANILINE PRODUCTS, INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3950130-A | THIAZOLE-AZO DYES AND THE COLORATION OF POLYESTER TEXTILE FIBERS THEREWITH | AMERICAN ANILINE PRODUCTS, INC. (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034763-A1 | COMPOSITE TEXTILES AND ARTICLES OF FOOTWEAR FORMED THEREFROM | PLOD1, COL14A1, COL1A1 | USP2 2075/4885TSHR 3994/4885TP53 1569/4885 |
| US-20260137174-A1 | SOLE STRUCTURES, AND ARTICLES OF FOOTWEAR FORMED THEREFROM | ETF1, EEF1A1, EEF2 | USP2 2639/4885TSHR 978/4885TP53 4401/4885 |
| US-12532945-B2 | Sole structures, and articles of footwear formed therefrom | ETF1, TERF2, GFRA2 | USP2 1921/4885TSHR 1052/4885TP53 3776/4885 |
| US-12528939-B2 | Filled polymeric resin materials and methods of making | TERB1, POT1, MTREX | USP2 2374/4885TSHR 871/4885TP53 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.