Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.55 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479773 | 0.87 | KDM4E (0.47) | KDM4EAPOBEC3GEHMT2EHMT1PDE7A | |
| SCHEMBL177702 | 0.85 | KDM4E (0.69) | KDM4EAPOBEC3GPDE7AKMT2AMAPT | |
| SCHEMBL21111965 | 0.85 | KDM4E (0.45) | KDM4EAPOBEC3GEHMT2EHMT1PDE7A | |
| SCHEMBL21111966 | 0.83 | KDM4E (0.43) | KDM4EAPOBEC3GEHMT2EHMT1PDE7A | |
| SCHEMBL11825400 | 0.82 | EHMT2 (0.81) | KDM4EAPOBEC3GEHMT2EHMT1KMT2A | |
| SCHEMBL28888688 | 0.80 | MAPT (0.56) | KDM4EKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL29523967 | 0.80 | MAPT (0.56) | KDM4EKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL12575467 | 0.80 | HTR2A (0.54) | KDM4EKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL8729226 | 0.79 | ALDH1A1 (0.62) | PDE7AKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL223594 | 0.78 | MEN1 (0.59) | KMT2AMAPTMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361260-A1 | NUCLEOTIDE ANALOGUES | SINGULAR GENOMICS SYSTEMS INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-12215122-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2025-02-04 | — | — | US | disclosed |
| US-20240400602-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-12-05 | — | — | US | disclosed |
| US-12145960-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2024-11-19 | — | — | US | disclosed |
| US-20240316036-A1 | DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-09-26 | — | — | US | disclosed |
| US-20240269156-A1 | DISULFIDE CONTAINING THERAPEUTICS | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-08-15 | — | — | US | disclosed |
| US-20240174709-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-05-30 | — | — | US | disclosed |
| US-11958877-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2024-04-16 | — | — | US | disclosed |
| US-11878993-B2 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2024-01-23 | — | — | US | disclosed |
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12215122-B2 | Nucleotide analogues | NUDT1, POLN, TYMP | KDM4E 3976/4885APOBEC3G 226/4885EHMT2 2494/4885 |
| US-20240400602-A1 | NUCLEOTIDE ANALOGUES | ADAR, NUDT1, NSUN2 | KDM4E 3158/4885APOBEC3G 236/4885EHMT2 938/4885 |
| US-20240316036-A1 | DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS | GPX1, GPX4, PDIA4 | KDM4E 4818/4885APOBEC3G 4047/4885EHMT2 2946/4885 |
| US-20250361260-A1 | NUCLEOTIDE ANALOGUES | ADAR, NUDT1, NSUN2 | KDM4E 3158/4885APOBEC3G 236/4885EHMT2 938/4885 |
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | KDM4E 4194/4885APOBEC3G 437/4885EHMT2 2878/4885 |
| US-20240269156-A1 | DISULFIDE CONTAINING THERAPEUTICS | P4HB, PDIA5, PDIA4 | KDM4E 4343/4885APOBEC3G 2768/4885EHMT2 3151/4885 |
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | KDM4E 4194/4885APOBEC3G 437/4885EHMT2 2878/4885 |
| US-11958877-B2 | Nucleotide analogues | ITPA, POLB, NUDT1 | KDM4E 4194/4885APOBEC3G 437/4885EHMT2 2878/4885 |
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | KDM4E 4194/4885APOBEC3G 437/4885EHMT2 2878/4885 |
| US-20240174709-A1 | NUCLEOTIDE ANALOGUES | NUDT1, POLN, TYMP | KDM4E 3976/4885APOBEC3G 226/4885EHMT2 2494/4885 |
| US-11878993-B2 | Nucleotide analogues | ITPA, POLB, NUDT1 | KDM4E 4194/4885APOBEC3G 437/4885EHMT2 2878/4885 |
| US-12145960-B2 | Nucleotide analogues | ITPA, POLB, NUDT1 | KDM4E 4194/4885APOBEC3G 437/4885EHMT2 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.