Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | CTSG | P08311 | 2/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.30 |
| ▸ | CMA1 | P23946 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070665 | 0.81 | MMP1 (0.34) | MEN1GAAKMT2APTGS1KCNH2 | |
| SCHEMBL29029802 | 0.81 | CA2 (0.50) | MAPK1CA2PRSS1CTSGCTRB1 | |
| SCHEMBL333214 | 0.79 | MEN1 (0.32) | MEN1GAAKMT2AMAPK1CA2 | |
| SCHEMBL793739 | 0.79 | CPB2 (0.46) | MEN1KMT2ACYP2D6FOLH1 | |
| SCHEMBL2400833 | 0.79 | GSR (0.48) | FOLH1 | |
| SCHEMBL3647951 | 0.79 | MEN1 (0.32) | MEN1GAAKMT2AMAPK1CA2 | |
| SCHEMBL9995723 | 0.79 | MMP3 (0.39) | MEN1GAAKMT2APTGS1KCNH2 | |
| SCHEMBL3659774 | 0.78 | PRSS1 (0.35) | MEN1GAAKMT2AFOLH1MAPK1 | |
| SCHEMBL4352303 | 0.77 | MEN1 (0.43) | MEN1GAAKMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL224143 | 0.76 | ALDH1A1 (0.37) | MEN1GAAKMT2ASMN1; SMN2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189679-A1 | CROSSLINKED POLYALLYLAMINE OR ACID ADDITION SALT THEREOF, AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2168992-A1 | CROSSLINKED POLYALLYLAMINE OR ACID ADDITION SALT THEREOF, AND USE THEREOF FOR MEDICAL PURPOSES | Toray Industries, Inc. (JP) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189679-A1 | CROSSLINKED POLYALLYLAMINE OR ACID ADDITION SALT THEREOF, AND USE THEREOF FOR MEDICAL PURPOSES | SLC6A12, SLC20A1, SLC20A2 | MEN1 939/4885GAA 749/4885KMT2A 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.