SCHEMBL3022641

SCHEMBL3022641

CSc1cccc(CC#N)c1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.49
MMP3 P08254 1/20 0.46
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
FFAR1 O14842 1/20 0.37
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300254 0.81 ENPP2 (0.46) ENPP2MMP3KDM4ETDP1MEN1
SCHEMBL6267276 0.81 MAPT (0.42) KDM4EMEN1KMT2AMAPTRECQL
SCHEMBL10547556 0.79 HTR2C (0.56) ENPP2MMP3KDM4ETDP1MEN1
SCHEMBL237972 0.79 ENPP2 (0.63) ENPP2MMP3KDM4ETDP1MEN1
Benzene SCHEMBL5438521 0.77 ENPP2 (0.61) ENPP2MMP3KDM4ETDP1MEN1
SCHEMBL11154063 0.77 ENPP2 (0.45) ENPP2MMP3KDM4ETDP1MEN1
SCHEMBL11155035 0.77 ENPP2 (0.45) ENPP2MMP3KDM4ETDP1MEN1
SCHEMBL3020802 0.76 AR (0.47) ENPP2MMP3KDM4ETDP1MEN1
SCHEMBL5022962 0.75 SIGMAR1 (0.50) MEN1KMT2AMAPTRECQL
SCHEMBL3272193 0.75 SLC6A4 (0.47) MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250233-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2025-08-07 US disclosed
CN-115151553-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
EP-4519246-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE Prilenia Neurotherapeutics Ltd. (IL) 2025-03-12 EP disclosed
CN-119137100-A Process and intermediates for the preparation of pridopidine 普瑞尼亚神经治疗有限公司 2024-12-13 CN disclosed
WO-2023214412-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2023-11-09 WO disclosed
CN-115151553-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-10-04 CN disclosed
WO-2021143923-A1 BORONIC ACID DERIVATIVES 首药控股(北京)股份有限公司 2021-07-22 WO disclosed
US-20210188843-A1 QUINOLINE COMPOUNDS AND THEIR PREPARATION AND USE AS ANTIMALARIAL AGENTS THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-06-24 US disclosed
EP-2164825-B1 DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM SANOFI SA (FR) 2014-04-30 EP disclosed
CN-101679191-B Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them SANOFI AVENTIS SPA 2014-03-12 CN disclosed
US-20100204206-A1 Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them SANOFI-AVENTIS (FR) 2010-08-12 US disclosed
EP-2164825-A1 DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Sanofi-Aventis (FR) 2010-03-24 EP disclosed
WO-2008148468-A1 DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM SANOFI-AVENTIS (FR) 2008-12-11 WO disclosed
US-6812228-B2 TREATMENT OF PROGRESSIVE NEURODEGENERATIVE MOVEMENT DISORDERS CHARACTERIZED BY HYPOKINESIA, TREMOR, AND MUSCULAR RIGIDITY WARNER-LAMBERT COMPANY 2004-11-02 US disclosed
EP-1282625-B1 BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE WARNER LAMBERT CO (US) 2004-06-30 EP disclosed
US-20030220335-A1 Benzoxazines for use in the treatment of parkinson's disease WARNER-LAMBERT COMPANY 2003-11-27 US disclosed
EP-1282625-A1 BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE WARNER-LAMBERT COMPANY (US) 2003-02-12 EP disclosed
WO-2001085734-A1 BENZOXAZINES FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE WARNER-LAMBERT COMPANY (US) 2001-11-15 WO disclosed
US-5405826-A Herbicidal pyridopyridazinones and pyridopyridazinethiones RHONE POULENC AGRICULTURE LIMITED (GB) 1995-04-11 US disclosed
EP-0555957-A1 Pyrido 2,3-d pyridazine derivatives as herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1993-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204206-A1 Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them ATP2A1, ATP2A2, RYR2 ENPP2 1052/4885MMP3 4671/4885KDM4E 2822/4885
US-20250250233-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE QDPR, MAOB, DRD2 ENPP2 2535/4885MMP3 3718/4885KDM4E 2968/4885
US-20030220335-A1 Benzoxazines for use in the treatment of parkinson's disease PARK7, HAX1, SNCA ENPP2 743/4885MMP3 606/4885KDM4E 2991/4885
US-20210188843-A1 QUINOLINE COMPOUNDS AND THEIR PREPARATION AND USE AS ANTIMALARIAL AGENTS GLS2, RECQL, PYGL ENPP2 2131/4885MMP3 4124/4885KDM4E 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.