Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300218 | 0.72 | CCNE1 (0.43) | KDM4ENPC1RAB9ASPTLC1XDH | |
| SCHEMBL6355228 | 0.72 | AURKA (0.46) | AURKASYKTMIGD3L3MBTL1CD63 | |
| SCHEMBL2129234 | 0.72 | TNKS (0.43) | AURKASYKSPTLC1XDHSLC22A12 | |
| SCHEMBL20125121 | 0.66 | ACKR3 (0.43) | ALDH1A3AURKAKDM4ENPC1ALDH1A1 | |
| SCHEMBL9788686 | 0.64 | TNKS (0.46) | KDM4ENPC1ALDH1A1GAARAB9A | |
| SCHEMBL18613325 | 0.64 | DYRK1A (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1369156 | 0.64 | L3MBTL1 (0.51) | ALDH1A3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7337736 | 0.63 | TNKS (0.73) | AURKAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL454081 | 0.63 | SPTLC1 (0.53) | KDM4EALDH1A1GAASMN1; SMN2SPTLC1 | |
| SCHEMBL15828627 | 0.63 | TNKS (0.45) | ALDH1A3AURKASYKSPTLC1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216994-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216994-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | APBA1, APP, S100A4 | ALDH1A3 2637/4885AURKA 3959/4885KDM4E 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.