Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 6/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CD63 | P08962 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454081 | 0.76 | SPTLC1 (0.53) | TNKSHDAC6SPTLC1XDHSLC22A12 | |
| SCHEMBL3025899 | 0.72 | ALDH1A3 (0.39) | TNKSSPTLC1XDHSLC22A12SYK | |
| SCHEMBL4966520 | 0.70 | TRIM33 (0.43) | CYP1A2SYK | |
| SCHEMBL9788686 | 0.69 | TNKS (0.46) | TNKSHDAC6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14205190 | 0.68 | LMNA (0.55) | — | |
| SCHEMBL2128509 | 0.68 | ALDH1A1 (0.64) | — | |
| SCHEMBL5343582 | 0.68 | SPTLC1 (0.45) | SPTLC1XDHSLC22A12 | |
| SCHEMBL17066644 | 0.67 | BCHE (0.49) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20125121 | 0.67 | ACKR3 (0.43) | TNKSSPTLC1XDHSLC22A12TMIGD3 | |
| SCHEMBL1431759 | 0.66 | TNKS (0.47) | TNKSSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129375-B1 | IMIDAZO[1,2-A]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-04-25 | — | — | EP | claimed |