Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 3/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2898846 | 0.78 | XDH (0.37) | CDK2XDHSLC22A12PIK3R1PIK3CA | |
| SCHEMBL2900371 | 0.74 | CCNE2 (0.47) | CCNE1CDK2XDHSLC22A12CCNE2 | |
| SCHEMBL3025899 | 0.72 | ALDH1A3 (0.39) | XDHSLC22A12SPTLC1L3MBTL1TNKS | |
| SCHEMBL1369156 | 0.70 | L3MBTL1 (0.51) | CDK2XDHSLC22A12SPTLC1L3MBTL1 | |
| SCHEMBL15747098 | 0.68 | L3MBTL1 (0.49) | L3MBTL1TNKS | |
| SCHEMBL26254580 | 0.68 | L3MBTL1 (0.62) | L3MBTL1TNKS | |
| SCHEMBL28020112 | 0.67 | XDH (0.42) | XDHSLC22A12L3MBTL1KDM4E | |
| SCHEMBL454081 | 0.66 | SPTLC1 (0.53) | XDHSLC22A12SPTLC1L3MBTL1TNKS | |
| SCHEMBL5351052 | 0.66 | SPTLC1 (0.50) | XDHSLC22A12SPTLC1KDM4ENPC1 | |
| SCHEMBL20125121 | 0.66 | ACKR3 (0.43) | CCNE1CDK2XDHSLC22A12SPTLC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8277777-B2 | Compound having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2012-10-02 | — | — | US | disclosed |
| US-20100092387-A1 | Novel Compound Having Affinity For Amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100092387-A1 | Novel Compound Having Affinity For Amyloid | APP, SLC43A1, APBA1 | CCNE1 1785/4885CDK2 4399/4885XDH 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.