Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 11/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 10/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 9/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 9/20 | 1.00 |
| ▸ | GSK3B | P49841 | 12/20 | 0.63 |
| ▸ | GSK3A | P49840 | 10/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.63 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | THPO | P40225 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307772 | 0.79 | GSK3B (0.75) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL29361130 | 0.77 | GSK3B (1.00) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL30319828 | 0.76 | CDK5R1 (1.00) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL12413918 | 0.69 | CCNB2 (0.53) | CDK1CCNB1CCNB2CCNB3MEN1 | |
| Indirubin-3-Monoxime SCHEMBL29354191 | 0.69 | CDK5R1 (1.00) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL30278941 | 0.66 | GSK3B (1.00) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL29484209 | 0.64 | GSK3B (1.00) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL30319818 | 0.64 | GSK3B (0.83) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL29924508 | 0.63 | GSK3B (0.72) | CDK1CCNB1CCNB2CCNB3GSK3B | |
| SCHEMBL8011931 | 0.63 | GPR3 (0.64) | CDK1CCNB1CCNB2CCNB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596657-B2 | Use of AhR agonist for the preventive or curative treatment of metabolic syndrome and the associated disorders | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2023-03-07 | — | — | US | claimed |
| US-12516022-B2 | Derivatives of aryl hydrocarbon receptor agonists | AZORA THERAPEUTICS, INC. (US) | 2026-01-06 | — | — | US | disclosed |
| EP-4412991-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. (US) | 2024-08-14 | — | — | EP | disclosed |
| US-20240182416-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. | 2024-06-06 | — | — | US | disclosed |
| US-11834412-B2 | Derivatives of aryl hydrocarbon receptor agonists | AZORA THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230227408-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| WO-2023060268-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AZORA THERAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |
| EP-4114420-A1 | COPROCOCCUS BACTERIA FOR USE IN THE TREATMENT OF METABOLIC SYNDROME AND INFLAMMATORY BOWEL DISEASES | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (FR) | 2023-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227408-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AHR, ARNT, NR4A1 | CDK1 3473/4885CCNB1 2659/4885CCNB2 3335/4885 |
| US-11834412-B2 | Derivatives of aryl hydrocarbon receptor agonists | AHR, ARNT, NR4A1 | CDK1 3473/4885CCNB1 2659/4885CCNB2 3335/4885 |
| US-20240182416-A1 | DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS | AHR, ARNT, NR4A1 | CDK1 3473/4885CCNB1 2659/4885CCNB2 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.