Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15659500 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MEN1RAB9AKMT2AHSD17B10 | |
| SCHEMBL5608644 | 0.86 | HTR7 (0.37) | ALDH1A1EPHX1KDM4EMEN1RAB9A | |
| SCHEMBL15659124 | 0.85 | ALDH1A1 (0.39) | ALDH1A1EPHX1KDM4EMEN1RAB9A | |
| SCHEMBL15658703 | 0.82 | ALDH1A1 (0.37) | ALDH1A1EPHX1KDM4EMEN1RAB9A | |
| SCHEMBL160594 | 0.82 | ALDH1A1 (0.37) | ALDH1A1EPHX1KDM4EMEN1RAB9A | |
| SCHEMBL30391805 | 0.82 | ALDH1A1 (0.37) | ALDH1A1EPHX1KDM4EMEN1RAB9A | |
| SCHEMBL1315359 | 0.82 | ROCK2 (0.35) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15656937 | 0.81 | ALDH1A1 (0.36) | ALDH1A1EPHX1KDM4EMEN1RAB9A | |
| SCHEMBL164194 | 0.80 | ALDH1A1 (0.38) | ALDH1A1EPHX1HSD17B10MAPTMPI | |
| SCHEMBL31566355 | 0.80 | ALDH1A1 (0.38) | ALDH1A1EPHX1HSD17B10MAPTMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735581-B1 | COMPOSITION AND POLYMER | ASAHI CHEMICAL IND (JP) | 2021-07-14 | — | — | EP | disclosed |
| WO-2019161649-A1 | 1-(8-ARYLNAPHTHYL)PHOSPHINE LIGAND AND PREPARATION METHOD THEREFOR, AND PHOSPHINE GOLD COMPLEX AND USE | 华中师范大学 | 2019-08-29 | — | — | WO | disclosed |
| US-9738757-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| CN-103502315-B | Composition and polymer | 旭化成株式会社 | 2016-08-17 | — | — | CN | disclosed |
| US-20160222168-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-08-04 | — | — | US | disclosed |
| CN-105754099-A | Composition and polymer | 旭化成株式会社 | 2016-07-13 | — | — | CN | disclosed |
| US-9334371-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| EP-2735581-A1 | COMPOSITION AND POLYMER | Asahi Kasei Chemicals Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |
| US-20140121293-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-05-01 | — | — | US | disclosed |
| CN-103502315-A | Composition and polymer | ASAHI KASEI CHEMICALS CORP | 2014-01-08 | — | — | CN | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| EP-2076512-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-07-08 | — | — | EP | disclosed |
| US-20080200729-A1 | Preparation of Aryl Phosphines | RHODIA UK LIMITED (GB) | 2008-08-21 | — | — | US | disclosed |
| US-20080200729-A1 | Preparation of Aryl Phosphines | RHODIA UK LIMITED (GB) | 2008-08-21 | — | — | US | disclosed |
| US-20080200729-A1 | Preparation of Aryl Phosphines | RHODIA UK LIMITED (GB) | 2008-08-21 | — | — | US | disclosed |
| WO-2008044022-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2008-04-17 | — | — | WO | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1673378-A1 | PREPARATION OF ARYL PHOSPHINES | Rhodia UK Limited (GB) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005023823-A1 | PREPARATION OF ARYL PHOSPHINES | RHODIA UK LIMITED (GB) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200729-A1 | Preparation of Aryl Phosphines | PRXL2A, PRDX1, TPO | ALDH1A1 3530/4885EPHX1 321/4885KDM4E 3721/4885 |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | THEM6, SOD1, SLC30A6 | ALDH1A1 2074/4885EPHX1 3052/4885KDM4E 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.