Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
| ▸ | CD40LG | P29965 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399908 | 1.00 | PRMT1 (0.47) | PRMT1CARM1CD40CD40LGPHLPP2 | |
| SCHEMBL15544404 | 0.88 | CD40 (0.43) | PRMT1CARM1CD40CD40LGPHLPP2 | |
| SCHEMBL14388951 | 0.88 | CD40 (0.43) | PRMT1CARM1CD40CD40LGPHLPP2 | |
| SCHEMBL15545271 | 0.84 | HPSE (0.41) | ENPP2MEN1KMT2APOLBGRK2 | |
| SCHEMBL15545273 | 0.84 | HPSE (0.41) | ENPP2MEN1KMT2APOLBGRK2 | |
| SCHEMBL15544630 | 0.83 | PRMT1 (0.60) | PRMT1CARM1CD40CD40LGPHLPP2 | |
| SCHEMBL15544626 | 0.83 | PRMT1 (0.60) | PRMT1CARM1CD40CD40LGPHLPP2 | |
| SCHEMBL29462936 | 0.83 | PRMT1 (0.60) | PRMT1CARM1CD40CD40LGPHLPP2 | |
| SCHEMBL13924738 | 0.81 | CYP1A2 (0.44) | CD40CD40LGPHLPP2ENPP2MEN1 | |
| SCHEMBL27789115 | 0.77 | PRMT1 (0.54) | PRMT1CARM1CD40CD40LGPHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390708-B1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO KGAA (DE) | 2023-04-05 | — | — | EP | disclosed |