Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 7/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545273 | 1.00 | HPSE (0.41) | HPSEENPP2POLBKMT2AP2RX1 | |
| SCHEMBL12189947 | 0.88 | ENPP2 (0.47) | HPSEENPP2KMT2AAPEX1RECQL | |
| SCHEMBL30399908 | 0.84 | PRMT1 (0.47) | ENPP2POLBKMT2ATDP1ALDH1A1 | |
| SCHEMBL30338211 | 0.84 | PRMT1 (0.47) | ENPP2POLBKMT2ATDP1ALDH1A1 | |
| SCHEMBL12189930 | 0.83 | ENPP2 (0.51) | HPSEENPP2KMT2AAPEX1RECQL | |
| Lithium Ion SCHEMBL30338038 | 0.82 | ENPP2 (0.46) | HPSEENPP2POLBKMT2AAPEX1 | |
| SCHEMBL15545270 | 0.75 | ENPP2 (0.48) | ENPP2KMT2AAPEX1TDP1ALDH1A1 | |
| SCHEMBL14615367 | 0.75 | ENPP2 (0.48) | ENPP2KMT2AAPEX1TDP1ALDH1A1 | |
| SCHEMBL14388951 | 0.73 | CD40 (0.43) | ENPP2KMT2ATDP1ALDH1A1MEN1 | |
| SCHEMBL15544404 | 0.73 | CD40 (0.43) | ENPP2KMT2ATDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877538-B1 | HOME FABRIC DYE PRODUCT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | claimed |
| EP-2877538-A1 | HOME FABRIC DYE PRODUCT | Punch Industries (IE) | 2015-06-03 | — | — | EP | claimed |
| WO-2014006132-A1 | HOME FABRIC DYE PRODUCT | PUNCH INDUSTRIES (IE) | 2014-01-09 | — | — | WO | claimed |
| EP-3390708-B1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO KGAA (DE) | 2023-04-05 | — | — | EP | disclosed |
| EP-3390708-A1 | CONSUMER UNIT FOR DYEING TEXTILE | Henkel AG & Co. KGaA (DE) | 2018-10-24 | — | — | EP | disclosed |
| EP-2877538-B1 | HOME FABRIC DYE PRODUCT | HENKEL AG & CO KGAA (DE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2017102314-A1 | CONSUMER UNIT FOR DYEING TEXTILE | HENKEL AG & CO. KGAA (DE) | 2017-06-22 | — | — | WO | disclosed |
| EP-2877538-A1 | HOME FABRIC DYE PRODUCT | Punch Industries (IE) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014006132-A1 | HOME FABRIC DYE PRODUCT | PUNCH INDUSTRIES (IE) | 2014-01-09 | — | — | WO | disclosed |