Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 19/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034636 | 0.78 | HSP90AA1 (0.38) | PIM1 | |
| SCHEMBL13177798 | 0.78 | HTR4 (0.41) | PIM1 | |
| SCHEMBL2952943 | 0.77 | MAP2K7 (0.45) | PDE7APDE7B | |
| SCHEMBL2946044 | 0.72 | MAPT (0.43) | PDE7A | |
| SCHEMBL2946218 | 0.69 | CHEK1 (0.47) | PDE7APDE7B | |
| SCHEMBL2947301 | 0.69 | PDE2A (0.48) | — | |
| SCHEMBL2950517 | 0.67 | ADORA2A (0.40) | PDE7APDE7BPDE4D | |
| SCHEMBL2951931 | 0.67 | PRKDC (0.42) | — | |
| SCHEMBL2954598 | 0.67 | DHFR (0.43) | — | |
| SCHEMBL2956342 | 0.66 | PDE4B (0.42) | PDE7APDE7BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |