Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952943 | 0.90 | MAP2K7 (0.45) | PDE7ATTKPRKDCFYNINSR | |
| SCHEMBL2953601 | 0.86 | PARP1 (0.42) | SMN1; SMN2CDK1CDK2MEN1KMT2A | |
| SCHEMBL2951931 | 0.85 | PRKDC (0.42) | MAPTSMN1; SMN2ALDH1A1MAPK1DHFR | |
| SCHEMBL2946368 | 0.80 | PRKDC (0.40) | MAPTSMN1; SMN2DHFRPRKDCCDK1 | |
| SCHEMBL2953053 | 0.76 | ADK (0.42) | MAPTSMN1; SMN2DHFRPRKDCCDK1 | |
| SCHEMBL2946049 | 0.75 | DHFR (0.42) | MAPTSMN1; SMN2TDP1LMNAALDH1A1 | |
| SCHEMBL2946549 | 0.73 | CDK1 (0.32) | SMN1; SMN2DHFRCDK1CDK2KDM4E | |
| SCHEMBL2952310 | 0.72 | NPC1 (0.50) | SMN1; SMN2ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL3034624 | 0.72 | PDE7A (0.41) | PDE7A | |
| SCHEMBL1912077 | 0.72 | LGMN (0.56) | MAPTSMN1; SMN2TDP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |