Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP5 | Q16690 | 4/20 | 1.00 |
| ▸ | DUSP6 | Q16828 | 1/20 | 1.00 |
| ▸ | ING2 | Q9H160 | 3/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PKLR | P30613 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664952 | 0.92 | DUSP5 (0.85) | DUSP5DUSP6ING2PTPN1PKLR | |
| SCHEMBL15397115 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| SCHEMBL15397119 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| SCHEMBL19203101 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| SCHEMBL29486957 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| SCHEMBL29664959 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| SCHEMBL29486958 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| SCHEMBL29776588 | 0.77 | ING2 (1.00) | DUSP5DUSP6ING2PTPRBLMNA | |
| Water SCHEMBL30366794 | 0.76 | ING2 (0.95) | DUSP5DUSP6ING2PTPRBLMNA | |
| Water SCHEMBL31084794 | 0.76 | ING2 (0.95) | DUSP5DUSP6ING2PTPRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624163-B2 | Ionomers with macrocyclic moieties for ion conductivity and permselectivity | NUTECH VENTURES (US) | 2026-05-12 | — | — | US | disclosed |
| US-20230225988-A1 | ANTIVIRAL USE OF CALIXARENES | CEBINA GmbH (AT) | 2023-07-20 | — | — | US | disclosed |
| US-20230220158-A1 | IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY | NATIONAL SCIENCE FOUNDATION | 2023-07-13 | — | — | US | disclosed |
| EP-4167983-A1 | ANTIVIRAL USE OF CALIXARENES | CEBINA GmbH (AT) | 2023-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225988-A1 | ANTIVIRAL USE OF CALIXARENES | CALU, CANX, CTSA | DUSP5 1815/4885DUSP6 1390/4885ING2 4014/4885 |
| US-12624163-B2 | Ionomers with macrocyclic moieties for ion conductivity and permselectivity | ZYX, CANX, GJB2 | DUSP5 4241/4885DUSP6 3985/4885ING2 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.