SCHEMBL30423979

SCHEMBL30423979

FC(F)(F)C(F)(F)c1ccnc(CCl)n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MBOAT4 Q96T53 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594754 0.77 SYK (0.36) MBOAT4
SCHEMBL2014949 0.75 GABRA1 (0.38)
SCHEMBL8751966 0.71 TRPV4 (0.33)
SCHEMBL28173201 0.71 SORT1 (0.36)
SCHEMBL4953533 0.70
SCHEMBL24253744 0.69
SCHEMBL21067202 0.67
SCHEMBL3289117 0.67 SORD (0.31)
SCHEMBL17870 0.67 CTSK (0.41)
SCHEMBL18581 0.67 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157404-A Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof 诺华股份有限公司 2023-05-23 CN disclosed