Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594754 | 0.77 | SYK (0.36) | MBOAT4 | |
| SCHEMBL2014949 | 0.75 | GABRA1 (0.38) | — | |
| SCHEMBL8751966 | 0.71 | TRPV4 (0.33) | — | |
| SCHEMBL28173201 | 0.71 | SORT1 (0.36) | — | |
| SCHEMBL4953533 | 0.70 | — | — | |
| SCHEMBL24253744 | 0.69 | — | — | |
| SCHEMBL21067202 | 0.67 | — | — | |
| SCHEMBL3289117 | 0.67 | SORD (0.31) | — | |
| SCHEMBL18581 | 0.67 | LMNA (0.38) | — | |
| SCHEMBL17870 | 0.67 | CTSK (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | disclosed |