Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CD38 | P28907 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428491 | 0.81 | KDM4E (0.56) | KDM4ECRHR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27937552 | 0.80 | KDM4E (0.54) | KDM4ECRHR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL26766431 | 0.79 | CRHR1 (0.58) | KDM4EPDE10ACRHR1ALDH1A1HPGD | |
| SCHEMBL29555308 | 0.78 | CRHR1 (0.55) | KDM4EPDE10ACRHR1ALDH1A1HPGD | |
| SCHEMBL2875528 | 0.78 | CRHR1 (0.55) | KDM4EPDE10ACRHR1ALDH1A1HPGD | |
| SCHEMBL30503376 | 0.78 | CD38 (0.48) | KDM4EALDH1A1HPGDHSD17B10CD38 | |
| SCHEMBL29015162 | 0.77 | CRHR1 (0.53) | KDM4EPDE10ACRHR1ALDH1A1HPGD | |
| SCHEMBL30401658 | 0.77 | CRHR1 (0.53) | KDM4EPDE10ACRHR1ALDH1A1HPGD | |
| SCHEMBL11430744 | 0.76 | SLC40A1 (0.54) | KDM4EPDE10AALDH1A1HPGDHSD17B10 | |
| SCHEMBL11619165 | 0.75 | KDM4E (0.65) | KDM4EPDE10ACRHR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20230276708-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-08-31 | — | — | US | disclosed |
| US-11711970-B2 | Organic electroluminescent device | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | KDM4E 4253/4885PDE10A 4373/4885CRHR1 126/4885 |
| US-20230276708-A1 | Polycyclic aromatic compound | ACVR1B, XDH, AHR | KDM4E 583/4885PDE10A 4125/4885CRHR1 244/4885 |
| US-11711970-B2 | Organic electroluminescent device | LEF1, AOC2, AFF2 | KDM4E 1417/4885PDE10A 3119/4885CRHR1 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.