Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27530286 | 0.85 | PTGS2 (0.35) | ENPP2G6PDIDESMN1; SMN2PTGS2 | |
| SCHEMBL15094420 | 0.85 | PTGS2 (0.37) | ENPP2PTGS2LMNA | |
| SCHEMBL27224554 | 0.84 | ENPP2 (0.32) | ENPP2PTGS2 | |
| SCHEMBL1528953 | 0.84 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL28987499 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2PTGS2LMNA | |
| SCHEMBL1334156 | 0.78 | ENPP2 (0.48) | ENPP2G6PDIDESMN1; SMN2PTGS2 | |
| SCHEMBL3193914 | 0.78 | ENPP2 (0.39) | ENPP2G6PDIDESMN1; SMN2PTGS2 | |
| SCHEMBL27224546 | 0.74 | NR1H2 (0.34) | — | |
| SCHEMBL27224556 | 0.74 | PTGS2 (0.40) | SMN1; SMN2PTGS2LMNA | |
| SCHEMBL17290775 | 0.74 | PSIP1 (0.46) | SMN1; SMN2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904350-B1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 2023-08-23 | — | — | EP | claimed |
| EP-3904350-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | claimed |
| US-20210147387-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | US | claimed |
| EP-3774778-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-02-17 | — | — | EP | claimed |
| WO-2019197468-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-17 | — | — | WO | claimed |
| US-10314831-B2 | RAC1 inhibitors of neurofibroma formation | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2019-06-11 | — | — | US | claimed |
| US-20160317516-A1 | RAC1 INHIBITORS OF NEUROFIBROMA FORMATION | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2016-11-03 | — | — | US | claimed |
| WO-2015108966-A2 | RAC1 INHIBITORS OF NEUROFIBROMA FORMATION | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-23 | — | — | WO | claimed |
| US-4073783-A | PENICILLINS | PFIZER INC. (US) | 1978-02-14 | — | — | US | claimed |
| EP-3904350-B1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-3904349-A2 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}HETEROCYCLYL AMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |
| EP-3904350-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |
| US-20210147387-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | US | disclosed |
| EP-3774778-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-02-17 | — | — | EP | disclosed |
| US-8232420-B2 | Asymmetric catalyst and process for preparing optically active alcohols using the same | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2012-07-31 | — | — | US | disclosed |
| US-20100261924-A1 | ASYMMETRIC CATALYST AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOLS USING THE SAME | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-2239057-A1 | Asymmetric catalyst and process for preparing optically active alcohols using the same | Kanto Kagaku Kabushiki Kaisha (JP) | 2010-10-13 | — | — | EP | disclosed |
| EP-0866367-A2 | Radiation sensitive composition | JSR Corporation (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-4920029-A | INCORPORATING A NONDIFFUSING HYDRAZINE DERIVATIVE AND LIGHT-INSENSITIVE HYDROPHILIC COLLOID; ANTISOILANTS; ELIMINATION OF BLACK SPOTS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| US-4824764-A | HIGH CONTRAST IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261924-A1 | ASYMMETRIC CATALYST AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOLS USING THE SAME | ADH1A, ADH1C, ADH5 | ENPP2 3728/4885G6PD 2976/4885IDE 1700/4885 |
| US-20210147387-A1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | CYP4F3, TARS2, H1-3 | ENPP2 1796/4885G6PD 4014/4885IDE 2641/4885 |
| US-10314831-B2 | RAC1 inhibitors of neurofibroma formation | RAC1, HRAS, KRAS | ENPP2 1675/4885G6PD 3000/4885IDE 4427/4885 |
| US-20160317516-A1 | RAC1 INHIBITORS OF NEUROFIBROMA FORMATION | RAC1, HRAS, KRAS | ENPP2 1675/4885G6PD 3000/4885IDE 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.