Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 8/20 | 0.33 |
| ▸ | PKLR | P30613 | 6/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174383 | 0.73 | PKM (0.55) | GRIA1GRIA2GRIA4GRIK5PKM | |
| SCHEMBL11086435 | 0.71 | MEN1 (0.60) | GRIA1GRIA2GRIA4GRIK5PKM | |
| SCHEMBL30995454 | 0.70 | MMP1 (0.43) | PKMMMP1MMP2MMP9MMP12 | |
| SCHEMBL30020048 | 0.69 | HSD17B10 (0.54) | GRIA1GRIA2GRIA4GRIK5PKM | |
| SCHEMBL30753174 | 0.69 | TRAP1 (0.40) | MMP1MMP2MMP9MMP12THRB | |
| SCHEMBL9540945 | 0.69 | GRIA1 (0.56) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL12294592 | 0.69 | GRIA1 (0.51) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL24781783 | 0.68 | THRA (0.35) | GRIA1GRIA2GRIA4GRIK5PKM | |
| SCHEMBL30529262 | 0.68 | P2RX7 (0.36) | BTKPKMPKLRHSP90AA1HSP90AB1 | |
| SCHEMBL24780765 | 0.67 | THRB (0.43) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165459-A1 | COMPOUNDS AS SARS-COV-2 INHIBITORS | FOCHON BIOSCIENCES , LTD. (CN) | 2023-09-07 | — | — | WO | disclosed |