Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535082 | 0.98 | TSHR (0.44) | TSHRHIF1AFAAHTRPV1GRM4 | |
| Hydrochloric Acid SCHEMBL29896516 | 0.95 | TSHR (0.42) | TSHRHIF1AFAAHTRPV1GRM4 | |
| Bromide SCHEMBL30547353 | 0.95 | TSHR (0.42) | TSHRHIF1AFAAHTRPV1GRM4 | |
| SCHEMBL22548448 | 0.90 | — | — | |
| SCHEMBL12491069 | 0.79 | — | — | |
| Iodide SCHEMBL28870826 | 0.78 | TSHR (0.44) | TSHRHIF1AFAAHTRPV1ACLY | |
| Hydrochloric Acid SCHEMBL13729232 | 0.77 | — | — | |
| SCHEMBL1784550 | 0.77 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ACLY | |
| SCHEMBL5443031 | 0.76 | GRM4 (0.41) | GRM4 | |
| SCHEMBL1783238 | 0.75 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035392-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2026-02-05 | — | — | US | disclosed |
| US-12466846-B2 | Siloxane derivatives of amino acids having surface-active properties | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-11-11 | — | — | US | disclosed |
| US-20250057955-A1 | SURFACTANTS FOR USE IN HEALTHCARE PRODUCTS | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-20 | — | — | US | disclosed |
| US-20250057749-A1 | SURFACTANTS FOR USE IN PERSONAL CARE AND COSMETIC PRODUCTS | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-20 | — | — | US | disclosed |
| US-20250051643-A1 | SURFACTANTS FOR ELECTRONICS | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | US | disclosed |
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057749-A1 | SURFACTANTS FOR USE IN PERSONAL CARE AND COSMETIC PRODUCTS | CUTA, SMURF1, PLOD3 | TSHR 1489/4885HIF1A 3018/4885FAAH 1713/4885 |
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | BCAT1, PCMT1, LTN1 | TSHR 4450/4885HIF1A 3932/4885FAAH 4214/4885 |
| US-20250051643-A1 | SURFACTANTS FOR ELECTRONICS | STOM, ESPL1, SMURF1 | TSHR 3113/4885HIF1A 3418/4885FAAH 1457/4885 |
| US-12466846-B2 | Siloxane derivatives of amino acids having surface-active properties | BCAT1, PCMT1, LTN1 | TSHR 4450/4885HIF1A 3932/4885FAAH 4214/4885 |
| US-20260035392-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | BCAT1, BCAT2, SLC43A1 | TSHR 2235/4885HIF1A 3158/4885FAAH 2934/4885 |
| US-20250057955-A1 | SURFACTANTS FOR USE IN HEALTHCARE PRODUCTS | S100P, DSG1, TMSB10 | TSHR 3295/4885HIF1A 2086/4885FAAH 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.