SCHEMBL31546464

SCHEMBL31546464

Cc1ccc(CN2CC(CNC(=O)C3CCN(c4nc(-c5ccc(C#N)cc5)no4)CC3)CC2=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ RXFP3 Q9NSD7 8/20 0.51
▸ MAPT P10636 3/20 0.49
▸ ACHE P22303 1/20 0.44
▸ LMNA P02545 2/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584909 0.90 RXFP3 (0.49) RXFP3MAPTACHELMNA
SCHEMBL30584823 0.87 ACHE (0.51) MAPTACHELMNAMEN1KMT2A
SCHEMBL30584763 0.79 MAPT (0.45) MAPTACHELMNAMEN1KMT2A
SCHEMBL30585036 0.79 MAPT (0.52) MAPTACHELMNA
SCHEMBL25435779 0.78 MAPT (0.53) MAPTLMNAMEN1KMT2A
SCHEMBL25433137 0.78 CCR5 (0.53) MAPTLMNAMEN1KMT2A
SCHEMBL30584794 0.77 MAPT (0.48) MAPTLMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL25439425 0.77 MAPT (0.53) MAPTLMNAMEN1KMT2A
SCHEMBL25437981 0.76 LMNA (0.59) MAPTLMNAMEN1KMT2A
SCHEMBL30584949 0.76 MEN1 (0.49) MAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 RXFP3 4798/4885MAPT 2999/4885ACHE 4880/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 RXFP3 4798/4885MAPT 2999/4885ACHE 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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