Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603596 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL416659 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL158053 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29652034 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL362333 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6337655 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6335926 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6842010 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29040265 | 0.83 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL11623286 | 0.83 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2AMEN1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868194-B2 | Process for the preparation of 21-hydroxy steroids with control of the epimeric distribution at the C-21 position | INDUSTRIALE CHIMICA S.R.L. (IT) | 2011-01-11 | — | — | US | claimed |
| EP-1809649-B1 | PROCESS FOR THE PREPARATION OF 21-HYDROXY STEROIDS WITH CONTROL OF THE EPIMERIC DISTRIBUTION AT THE C-21 POSITION | IND CHIMICA SRL (IT) | 2010-03-17 | — | — | EP | claimed |
| US-20080114180-A1 | Process for the Preparation of 21-Hydroxy Steroids with Control of the Epimeric Distribution at the C-21 Position | INDUSTRIALE CHIMICA S.R.L. (IT) | 2008-05-15 | — | — | US | claimed |
| EP-1809649-A1 | PROCESS FOR THE PREPARATION OF 21-HYDROXY STEROIDS WITH CONTROL OF THE EPIMERIC DISTRIBUTION AT THE C-21 POSITION | INDUSTRIALE CHIMICA S.r.l. (IT) | 2007-07-25 | — | — | EP | claimed |
| US-20070010676-A1 | Stereospecific enrichment of heterocyclic enantiomers | R.T. ALAMO VENTURES I, LLC | 2007-01-11 | — | — | US | claimed |
| US-7084275-B2 | Stereospecific enrichment of heterocyclic enantiomers | R. T. ALAMO VENTURES I, LLC (US) | 2006-08-01 | — | — | US | claimed |
| WO-2006045745-A1 | PROCESS FOR THE PREPARATION OF 21-HYDROXY STEROIDS WITH CONTROL OF THE EPIMERIC DISTRIBUTION AT THE C-21 POSITION | INDUSTRIALE CHIMICA S.R.L. (IT) | 2006-05-04 | — | — | WO | claimed |
| US-20040220218-A1 | Chlorinated heterocyclic compounds and methods of synthesis | R.T. ALAMO VENTURES I, LLC | 2004-11-04 | — | — | US | claimed |
| US-20040215016-A1 | Stereospecific enrichment of heterocyclic enantiomers | R.T. ALAMO VENTURES I, LLC | 2004-10-28 | — | — | US | claimed |
| US-6730790-B2 | INCLUDING RACEMIC MONOCHLOROFLOSEQUINAN, PURIFIED ENANTIOMERS OF MONOCHLOROFLOSEQUINAN AND SULFONE DERIVATIVE OF MONOCHLOROFLOSEQUINAN | R.T. ALAMO VENTURES I. LLC | 2004-05-04 | — | — | US | claimed |
| US-6649764-B2 | Racemization of flusequinan using triphenylphosphine and 10-camphorsulfonyl-oxaziridine to form racemic mixtures | R. T. ALAMO VENTURES I, LLC | 2003-11-18 | — | — | US | claimed |
| US-20030166677-A1 | CHLORINATED HETEROCYCLIC COMPOUNDS AND METHODS OF SYNTHESIS | R.T. ALAMO VENTURES I, LLC | 2003-09-04 | — | — | US | claimed |
| US-20030120075-A1 | Stereospecific enrichment of heterocyclic enantiomers | R.T. ALAMO ADVENTURES I, LLC | 2003-06-26 | — | — | US | claimed |
| US-12479830-B2 | Homopiperazinyl and homopiperidinyl quinazolin-4(3H)-one derivatives having multimodal activity against pain | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2025-11-25 | — | — | US | disclosed |
| WO-2025235761-A1 | REAGENTS AND PROCESSES FOR PREPARING OLIGONUCLEOTIDES | BIOGEN MA INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| EP-4588908-A1 | NEW PROSTACYCLIN FOR TREATING PULMONARY HYPERTENSION | Shanghai Forefront Pharma Co., Ltd. (CN) | 2025-07-23 | — | — | EP | disclosed |
| WO-1996025405-A1 | SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-22 | — | — | WO | disclosed |
| EP-0710223-A4 | SYNTHESIS OF TAXOL AND ITS DERIVATIVES | UNIV FLORIDA STATE (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0710223-A1 | SYNTHESIS OF TAXOL AND ITS DERIVATIVES | FLORIDA STATE UNIVERSITY (US) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003265-A1 | SYNTHESIS OF TAXOL AND ITS DERIVATIVES | FLORIDA STATE UNIVERSITY (US) | 1995-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220218-A1 | Chlorinated heterocyclic compounds and methods of synthesis | STS, SCLY, HCCS | SMN1; SMN2 4873/4885KMT2A 1092/4885MEN1 1262/4885 |
| US-20030166677-A1 | CHLORINATED HETEROCYCLIC COMPOUNDS AND METHODS OF SYNTHESIS | STS, SCLY, HCCS | SMN1; SMN2 4873/4885KMT2A 1092/4885MEN1 1262/4885 |
| US-20070010676-A1 | Stereospecific enrichment of heterocyclic enantiomers | CBR3, CBR1, QDPR | SMN1; SMN2 3859/4885KMT2A 3308/4885MEN1 3511/4885 |
| US-12479830-B2 | Homopiperazinyl and homopiperidinyl quinazolin-4(3H)-one derivatives having multimodal activity against pain | OPRD1, SIGMAR1, OPRK1 | SMN1; SMN2 2559/4885KMT2A 4116/4885MEN1 4434/4885 |
| US-20080114180-A1 | Process for the Preparation of 21-Hydroxy Steroids with Control of the Epimeric Distribution at the C-21 Position | CYP17A1, CYP21A2, HSD17B7 | SMN1; SMN2 3303/4885KMT2A 2463/4885MEN1 303/4885 |
| US-20040215016-A1 | Stereospecific enrichment of heterocyclic enantiomers | CBR3, POR, CBR1 | SMN1; SMN2 3953/4885KMT2A 3103/4885MEN1 3536/4885 |
| US-20030120075-A1 | Stereospecific enrichment of heterocyclic enantiomers | CBR3, POR, CBR1 | SMN1; SMN2 3953/4885KMT2A 3103/4885MEN1 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.