Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762714 | 0.77 | RAB9A (0.51) | POLBHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL3066168 | 0.77 | MPL (0.53) | POLBHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL30723291 | 0.77 | MAPT (0.54) | POLBMAPTNPC1RAB9ACYP1A2 | |
| SCHEMBL770898 | 0.71 | POLB (0.44) | POLBMAPTNPC1RAB9ACYP1A2 | |
| SCHEMBL10719025 | 0.71 | ALDH1A1 (0.61) | POLBHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL30723286 | 0.71 | TRPV4 (0.57) | POLBHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL30263272 | 0.69 | HSD17B10 (1.00) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL39119 | 0.69 | HSD17B10 (1.00) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL428793 | 0.68 | RAB9A (0.96) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16434193 | 0.68 | LMNA (0.71) | POLBHSD17B10MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486872-A | Mechanical ball milling synthesis method of aminothiazole compound | 浙江工业大学 | 2024-02-02 | — | — | CN | disclosed |