Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3355962 | 0.82 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL6399753 | 0.76 | SIGMAR1 (0.38) | GABRA1GABRB2FAAHCA1CA2 | |
| SCHEMBL4762075 | 0.70 | ALDH1A1 (0.39) | CA1CA2LMNACYP1A2CYP3A4 | |
| SCHEMBL28755427 | 0.69 | NPC1 (0.33) | SIGMAR1 | |
| SCHEMBL7778428 | 0.68 | PNMT (0.35) | CYP1A2CYP3A4HTR2BSIGMAR1 | |
| SCHEMBL10611980 | 0.68 | GABRA1 (0.56) | GABRA1GABRB2FAAHCA1CA2 | |
| SCHEMBL5158379 | 0.67 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL9062195 | 0.67 | HTR2A (0.36) | CA2LMNACYP1A2CYP3A4HPGD | |
| SCHEMBL2830663 | 0.67 | HTR2C (0.37) | LMNACYP3A4TSHRSLC6A2HTR2C | |
| Hydrochloric Acid SCHEMBL30769837 | 0.67 | HTR2A (0.36) | LMNACYP3A4SLC6A2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | disclosed |