SCHEMBL30773978

SCHEMBL30773978

COc1cccc(CC(=O)N2CCOc3c(-c4ccc(C#N)cc4)cncc32)c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 2/20 0.43
▸ RIPK1 Q13546 4/20 0.42
▸ EIF2AK3 Q9NZJ5 1/20 0.42
▸ NAAA Q02083 2/20 0.42
▸ TNIK Q9UKE5 2/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SIGMAR1 Q99720 1/20 0.39
▸ EGLN2 Q96KS0 2/20 0.39
▸ ROCK2 O75116 2/20 0.38
▸ ROCK1 Q13464 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ MAPKAPK2 P49137 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31635543 0.92 RAB9A (0.42) TNIKRAB9ASIGMAR1EGLN2ROCK2
SCHEMBL30773952 0.90 SMN1; SMN2 (0.42) FAAHNAAARAB9AALDH1A1MAPT
SCHEMBL30773980 0.89 RIPK1 (0.41) FAAHRIPK1EIF2AK3NAAAKDM4E
SCHEMBL30774028 0.87 NAAA (0.40) FAAHRIPK1EIF2AK3NAAAEGLN2
SCHEMBL30773988 0.87 NAAA (0.40) FAAHRIPK1EIF2AK3NAAA
SCHEMBL30774484 0.86 CYP11B2 (0.48) FAAHNAAAALDH1A1MAPTKMT2A
SCHEMBL30774900 0.86 TNIK (0.42) TNIKROCK2ROCK1KDM4EMEN1
SCHEMBL30774584 0.85 RIPK1 (0.48) RIPK1EIF2AK3RAB9ASIGMAR1EGLN2
SCHEMBL30774563 0.85 GPR142 (0.46) FAAHRIPK1EIF2AK3NAAAROCK2
SCHEMBL30774026 0.83 NAAA (0.40) FAAHEIF2AK3NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 FAAH 1677/4885RIPK1 3331/4885EIF2AK3 1947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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