SCHEMBL30773980

SCHEMBL30773980

Cc1cccc(CC(=O)N2CCOc3c(-c4ccc(C#N)cc4)cncc32)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 2/20 0.41
▸ EIF2AK3 Q9NZJ5 1/20 0.41
▸ NAAA Q02083 4/20 0.40
▸ FAAH O00519 3/20 0.40
▸ POLB P06746 1/20 0.40
▸ FNTA P49354 1/20 0.38
▸ FNTB P49356 1/20 0.38
▸ PGGT1B P53609 1/20 0.38
▸ SLC22A12 Q96S37 2/20 0.38
▸ CYP11B1 P15538 2/20 0.37
▸ CYP11B2 P19099 2/20 0.37
▸ UCHL1 P09936 1/20 0.36
▸ USP30 Q70CQ3 1/20 0.36
▸ GRM5 P41594 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774028 0.90 NAAA (0.40) RIPK1EIF2AK3NAAAFAAHFNTA
SCHEMBL30773988 0.90 NAAA (0.40) RIPK1EIF2AK3NAAAFAAHSLC22A12
SCHEMBL30774026 0.89 NAAA (0.40) EIF2AK3NAAAFAAHSLC22A12CYP11B1
SCHEMBL30773978 0.89 FAAH (0.43) RIPK1EIF2AK3NAAAFAAHKDM4E
SCHEMBL30774563 0.87 GPR142 (0.46) RIPK1EIF2AK3NAAAFAAHSLC22A12
SCHEMBL30774383 0.85 RIPK1 (0.46) RIPK1EIF2AK3POLBFNTAFNTB
SCHEMBL30773955 0.84 SCN2A (0.42) EIF2AK3NAAAFAAHFNTAFNTB
SCHEMBL30773967 0.84 NAAA (0.40) EIF2AK3NAAAFAAHSLC22A12CYP11B1
SCHEMBL30773965 0.84 FAAH (0.40) RIPK1NAAAFAAHFNTAFNTB
SCHEMBL30774857 0.82 SLC22A12 (0.40) SLC22A12CYP11B1CYP11B2UCHL1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 RIPK1 3331/4885EIF2AK3 1947/4885NAAA 1168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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