SCHEMBL30775606

SCHEMBL30775606

CCOP(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TAAR1 Q96RJ0 3/20 0.36
IDO1 P14902 2/20 0.36
AGXT P21549 2/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
MAPK1 P28482 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196443 0.87 CYP3A4 (0.39) L3MBTL1ALDH1A1TP53CYP3A4TDP1
SCHEMBL30356625 0.82 AGXT (0.38) ALDH1A1AGXT
SCHEMBL30775608 0.80 L3MBTL1 (0.40) L3MBTL1ALDH1A1HPGDKDM4ETP53
SCHEMBL11728040 0.79 KCNN4 (0.33) TP53CYP3A4TDP1
Biphenyl SCHEMBL27686986 0.78 ALDH1A1 (0.45) SMN1; SMN2MAPTL3MBTL1ALDH1A1NPC1
SCHEMBL8336303 0.77 ALDH1A1 (0.40) SMN1; SMN2MAPTL3MBTL1ALDH1A1NPC1
SCHEMBL10709571 0.76 ACHE (0.38) SMN1; SMN2MAPTALDH1A1TAAR1IDO1
SCHEMBL7778608 0.74 TDP1 (0.36) SMN1; SMN2MAPTL3MBTL1IDO1AGXT
SCHEMBL30356616 0.74 TP53 (0.39) SMN1; SMN2L3MBTL1ALDH1A1TAAR1IDO1
SCHEMBL11277499 0.74 LMNA (0.36) SMN1; SMN2ALDH1A1TAAR1IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN disclosed