Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 7/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801792 | 0.84 | HSD11B1 (0.36) | PANK3HSD11B1HTR2CHTR2BHTR2A | |
| SCHEMBL23574020 | 0.84 | USP30 (0.40) | KCNJ1KCNH2PRMT5WDR77PANK3 | |
| SCHEMBL30801806 | 0.83 | HTR2A (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801876 | 0.79 | DRD2 (0.38) | KCNH2HTR2CHTR2BHTR2A | |
| SCHEMBL30801851 | 0.75 | HTR2C (0.35) | KCNJ1KCNH2PRMT5WDR77HTR2C | |
| SCHEMBL30801878 | 0.75 | TAAR1 (0.39) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801854 | 0.73 | ZDHHC9 (0.38) | KCNH2 | |
| SCHEMBL30801824 | 0.72 | HSD11B1 (0.34) | HSD11B1HTR2CHTR2BHTR2A | |
| SCHEMBL30801735 | 0.72 | HTR2A (0.37) | HSD11B1HTR2CHTR2BHTR2A | |
| SCHEMBL23573989 | 0.70 | USP30 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |