Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801792 | 0.87 | HSD11B1 (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801878 | 0.85 | TAAR1 (0.39) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801851 | 0.84 | HTR2C (0.35) | KCNH2HTR2CHTR2BHTR2A | |
| SCHEMBL23574042 | 0.84 | USP30 (0.36) | DRD2DRD3KCNH2TACR1MRGPRX1 | |
| SCHEMBL30801858 | 0.84 | SLC6A2 (0.40) | SLC6A2SLC6A4HTR2CHTR2BHTR2A | |
| SCHEMBL30801824 | 0.81 | HSD11B1 (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801765 | 0.79 | KCNJ1 (0.35) | KCNH2HTR2CHTR2BHTR2A | |
| SCHEMBL30801854 | 0.78 | ZDHHC9 (0.38) | KCNH2 | |
| SCHEMBL30801735 | 0.77 | HTR2A (0.37) | SLC6A2HTR2CHTR2BHTR2A | |
| SCHEMBL30801745 | 0.75 | PAX8 (0.37) | DRD2DRD3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |