Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801876 | 0.87 | DRD2 (0.38) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801854 | 0.86 | ZDHHC9 (0.38) | — | |
| SCHEMBL30801878 | 0.86 | TAAR1 (0.39) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL30801851 | 0.86 | HTR2C (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801735 | 0.84 | HTR2A (0.37) | HSD11B1OPRD1HTR2CHTR2BHTR2A | |
| SCHEMBL30801765 | 0.84 | KCNJ1 (0.35) | HSD11B1HTR2CHTR2BHTR2APANK3 | |
| SCHEMBL23574088 | 0.82 | USP30 (0.37) | HSD11B1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30801824 | 0.82 | HSD11B1 (0.34) | HSD11B1HTR2CHTR2BHTR2A | |
| SCHEMBL30801858 | 0.77 | SLC6A2 (0.40) | HSD11B1OPRD1HTR2CHTR2BHTR2A | |
| SCHEMBL30801751 | 0.74 | KCNH2 (0.38) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |