Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801858 | 0.87 | SLC6A2 (0.40) | HTR2AHTR2CHTR2BALDH1A1SLC6A2 | |
| SCHEMBL30801854 | 0.86 | ZDHHC9 (0.38) | — | |
| SCHEMBL30801878 | 0.86 | TAAR1 (0.39) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL30801792 | 0.84 | HSD11B1 (0.36) | HTR2AHTR2CHTR2BOPRD1HSD11B1 | |
| SCHEMBL30801824 | 0.82 | HSD11B1 (0.34) | HTR2AHTR2CHTR2BHSD11B1 | |
| SCHEMBL23574138 | 0.78 | LMNA (0.38) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| SCHEMBL30801804 | 0.78 | HTR2C (0.42) | HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL30801806 | 0.77 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL30801876 | 0.77 | DRD2 (0.38) | HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL30801898 | 0.76 | HTR2C (0.37) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |