Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801792 | 0.86 | HSD11B1 (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801876 | 0.84 | DRD2 (0.38) | HTR2CHTR2BKCNH2HTR2A | |
| SCHEMBL23574004 | 0.83 | USP30 (0.39) | PRMT5WDR77KCNJ1KCNH2 | |
| SCHEMBL30801824 | 0.81 | HSD11B1 (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801854 | 0.79 | ZDHHC9 (0.38) | KCNH2 | |
| SCHEMBL30801878 | 0.79 | TAAR1 (0.39) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801735 | 0.77 | HTR2A (0.37) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801858 | 0.76 | SLC6A2 (0.40) | HTR2CHTR2BHTR2A | |
| SCHEMBL30801765 | 0.75 | KCNJ1 (0.35) | HTR2CHTR2BPRMT5WDR77KCNJ1 | |
| SCHEMBL30801751 | 0.70 | KCNH2 (0.38) | HTR2CHTR2BKCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |