Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.42 |
| ▸ | HTR2A | P28223 | 10/20 | 0.42 |
| ▸ | HTR2B | P41595 | 10/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23574091 | 0.82 | USP30 (0.41) | TACR1 | |
| SCHEMBL30986842 | 0.82 | USP30 (0.41) | TACR1 | |
| SCHEMBL30801858 | 0.79 | SLC6A2 (0.40) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL30801735 | 0.78 | HTR2A (0.37) | HTR2CHTR2AHTR2BSLC6A2 | |
| SCHEMBL30801878 | 0.77 | TAAR1 (0.39) | HTR2CHTR2AHTR2BTAAR1 | |
| SCHEMBL30801824 | 0.74 | HSD11B1 (0.34) | HTR2CHTR2AHTR2B | |
| SCHEMBL30801854 | 0.73 | ZDHHC9 (0.38) | KCNH2 | |
| SCHEMBL30801876 | 0.73 | DRD2 (0.38) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL30801898 | 0.72 | HTR2C (0.37) | HTR2CHTR2AHTR2BTAAR1 | |
| SCHEMBL30801810 | 0.72 | USP30 (0.35) | HTR2CHTR2AHTR2BTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |