Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801735 | 0.87 | HTR2A (0.37) | SLC6A2OPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL30801878 | 0.85 | TAAR1 (0.39) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL30801876 | 0.84 | DRD2 (0.38) | SLC6A2SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL30801824 | 0.81 | HSD11B1 (0.34) | HTR2AHTR2CHTR2BHSD11B1 | |
| SCHEMBL23574084 | 0.80 | NAAA (0.41) | SMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL30801804 | 0.79 | HTR2C (0.42) | SLC6A2SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL30801854 | 0.78 | ZDHHC9 (0.38) | — | |
| SCHEMBL30801898 | 0.78 | HTR2C (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL30801792 | 0.77 | HSD11B1 (0.36) | OPRD1HTR2AHTR2CHTR2BHSD11B1 | |
| SCHEMBL30801810 | 0.76 | USP30 (0.35) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |